Although this region contains two potential polyadenylation hexanucleotides AATAAA (located 1328 and 1407 nucleotides downstream of the last membrane exon), it appears that only the first site directs polyadenylation of the mature mRNA. The first AATAAA is followed by several sequences which may ...
The PolyA Cleavage Site and 3'-UTR Database (PACdb) is a web-accessible database that catalogs putative 3'-processing sites and 3'-UTR sequences for multiple organisms. Sites have been identified primarily via expressed sequence tag-genome alignments, enabling delineation of both the specificities...
Cavallaro Gennara,Licciardi Mariano,Stefano M D,et al.New self-assembling polyaspartamide-based brush copoly-mers obtained by atom transfer radical polymerization.Macromolecules. 2009Cavallaro Gennara; Licciardi Mariano; Stefano M D;.New self-assembling polyaspartamide-based brush copoly- mers ...
1. 多聚腺苷酸化特异性因子(CPSF)复合体参与切割:CPSF复合体识别并结合位于前体mRNA的3’端附近的多聚腺苷酸化信号(PAS)。 2. poly(A)聚合酶(PAP)进行多聚腺苷酸化:在PAP的作用下,Poly(A)尾与核多聚腺苷酸结合蛋白(PABPN)结合,形成成熟的mRNA。 Poly(A)尾的长度是如何参与基因表达调控的呢?Poly(A)...
Navrotsky, Thermo- dynamic and structural aspects of the polyamorphic transition in yttrium and other rare-earth aluminate liquids, Physica Part A 314 (2002) 379-390.Thermodynamic and structural aspects of the polyamorphic transition in yttrium and other rare-earth aluminate liquids[J] . Martin C...
Expression of a PD1 transgene is variegated in the absence of sequences 3′ to the polyA site.Helit, Cohen
The regulated production of um and us mRNA is dependent on the relative efficiencies of us poly(A) site usage and the cu4-to-M1 splice.Peterson, M LPerry, R P
Identification of a direct role of CPSF6 and a key cis‐acting motif in promoting TRIM9 proximal polyA site usagedoi:10.1096/fasebj.2022.36.S1.R5796Herron, Richard S.Kunisky, AlexanderHwang, Hun‐WayFASEB Journal
Berger, M.L.; Schodl, C.; Noe, C.R.: Inverse agonists at the polyamin-sensitive modulatory site of the NMDA receptor: 50-fold increase in potency by insertion of an aromatic ring into an alkanediamine chain. Eur. J. Med. Chem. (1998) 33, 3- 14...
(2005) PACdb: PolyA cleavage site and 30-UTR database. Bioinformatics, 21, 3691-3693.Joel H Graber,et al.PACdb: PolyA Cleavage Site and 3’-UTR Database. Bioinformatics . 2005Brockman,J.M., Singh,P., Liu,D., Quinlan,S., Salisbury,J. and Graber,J.H. (2005) PACdb: PolyA ...