(2014) Poly(carboxybetaine) nanomaterials enable long circulation and prevent polymer-specific antibody production. Nano Today 9, 10-16Yang W, Liu S, Bai T, Keefe AJ, Zhang L, Ella-Menye J-R, Li Y, Jiang S. Poly(carboxybe- taine) nanomaterials enable long circulation and prevent polymer...
This review compares two types of non-fouling polymers, the widely used non-ionic poly(ethylene glycol) (PEG) and the recently established zwitterionic poly(carboxybetaine) (PCB), for their use in creating stealth nanoparticles (NPs) for drug delivery and protein protection. While both types of ...
Here, we demonstrate the feasibility of a lightly crosslinked poly(carboxybetaine) hydrogel for use in whole blood, as opposite to the conventional wisdom of high packing density in surface coatings. Proteins are able to diffuse in and out of the matrix freely without being altered from their ...
We introduce a dual-functional biocompatible material based on zwitterionic poly(carboxybetaine methacrylate) (polyCBMA), which not only highly resists protein adsorption/cell adhesion, but also has abundant functional groups convenient for the immobilization of biological ligands, such as proteins. The du...
Retraction Note: Plasma protein adsorption to zwitterionic poly (carboxybetaine methacrylate) modified surfaces: chain chemistry and end-group effects on protein adsorption kinetics, adsorbed amounts and immunoblots.doi:10.1186/1559-4106-8-11RetractionThis article [1] has been retracted on request of ...
The synthesis of poly(e—caprolactone)一一poly (carboxybetaine methacrylate) (PC L—PC BMA ) Firstly,￡一CL (15 mL,8O mmo1),Sn(Oct)2(32.4 mg,0.08 mmo1) were added into an ampoule.Aft er three freeze—vacuum—thaw cycles,the mixture was sealed by fl ame under vacuum and placed in...
Poly(carboxybetaine)Zwitterionic polymerZwitterionic hydrogels based on poly(carboxybetaine) methacrylate (polyCBMA) were developed to protect implantable electrochemical glucose biosensors from biofouling in complex media. To enhance the linearity and sensitivity of the sensing profile, both physical and ...
Our new poly(carboxybetaine) has 84% carboxybetaine structures in the side chains, as determined by 1H NMR measurements. The presence of betaine structures in the side chains was confirmed by viscosity measurements.doi:10.1002/(SICI)1521-3927(19991101)20:113.0.CO;2-TJiro Nagaya...
The poly(carboxybetaine) with two methylene group between N+ and COO- is soluble both in water and aqueous salt solutions and with a mixed viscosimetric behaviour. Thus, the addition of salt (i.e., NaCl, CaCl2) leads to the decrease of the intrinsic viscosity but this decrease is greater...
Zwitterionic Poly-Carboxybetaine Coating Reduces Artificial Lung Thrombosis in Sheep and Rabbitsartificial lungthrombosiszwitterioncarboxybetaine34-dihydroxyphenylalanine (DOPA)Current artificial lungs fail in 1-4 weeks due to surface-induced thrombosis. Biomaterial coatings may be applied to anticoagulate ...