To 4 ml of lysozyme solution (3 mg/ml) in 50 pH 6.5 buffer (50 mM sodium phosphate/50 mM NaCl ) was added 20 mg of the N-succinimidyl ester of the PEG alkanoate and the progress of the reaction at 22° C. was monitored by capillary electrophoresis at a wavelength of 205 nm. The...
26915-72-0 Alias: Storage: 储存温度2-8°C
Preferably, the integer a in the general formula (1) is 1 from the viewpoint of the solubility of polymetalloxane to solvents. Thus, preferred examples of the R2R3N(O)agroup include an N-succinimidyloxy group, an N-phthalimidyloxy group, an N-(4-nitrophthalimidyl)oxy group, an N-(...
The latter gives access to a new subgeneration of α‐functional poly(2﹐xazoline)s (butyl ester, N﹉ydroxysuccinimidyl ester, furan) by Michael addition with commercial (meth)acrylates. The amenability of the mercapto﹑oly(2〆thylxazoline) for covalent surface patterning onto acrylated ...
In addition, two molecules of the polymer of this invention can also be linked to the amino acid lysine to form a di-substituted lysine, which can then be further activated with N-hydroxysuccinimide to form an active N-succinimidyl moiety (see, e.g., U.S. Pat. No. 5,932,462). All...
Succinimidyl “active esters”, such as PEG-OCH2—CO2—NHS, are commonly used forms of activated carboxylic acid PEGs, and they are prepared by reacting carboxylic acid PEGs with N-hydroxysuccinimide. PEG hydrogels, which are water-swollen gels, have been used for wound covering and drug deliver...