Among biomaterials used for non-viral gene delivery, poly(beta-amino ester)s (PBAEs), a class of synthetic, biodegradable polymers, have risen as a leading gene delivery vehicle that has been used for multiple applications in vitro and in vivo. Areas covered This review summarizes the key ...
Yliperttula, Poly(beta-amino ester)-DNA complexes: Time-resolved fluorescence and cellular transfection studies, J. Controlled Release, 2011, 154, 171-176.E. Vuorimaa, T. M. Ketola, J. J. Green, M. Hanzlikova, H. Lemmetyinen, R. Langer, D. G. Anderson, A. Urtti and M. Yli...
As such, one can now envisage that dendritic poly(β-amino ester)s could be more conducive for efficient gene transfection, because, unlike LPAEs with only two terminals, dendritic poly(β-amino ester)s contain multiple terminal units. The three-dimensional (3D) topological structure of dendritic...
A bioreducible linear poly(beta-amino ester) for siRNA delivery. Chem Commun 2013;49:5319e21.K.L. Kozielski, S.Y. Tzeng, J.J. Green, A bioreducible linear poly(b-amino ester) for siRNA delivery, Chem. Comm. 49 (2013) 5319-5321....
β-Cyclodextrin-poly(β-Amino Ester) Nanoparticles for Sustained Drug Delivery across the Blood-Brain Barrier. Biomacromolecules 2012, 13, 3533-3541. [CrossRef] [PubMed]Gil ES, Wu L, Xu L, Lowe TL. Beta-Cyclodextrin-Poly (Beta-Amino Ester) Nanoparticles for Sustained Dru...
pH- and temperature-sensitive PCL-grafted poly(beta-amino ester)-poly(ethylene glycol)-poly(beta-amino ester) copolymer hydrogels A series of poly( -caprolactone)-grafted poly( 尾 -amino ester)-poly(ethylene glycol)-poly( 尾 -amino ester) ((PAE- g -PCL)-PEG-(PAE- g -PCL)) copolymers...
ether,alcohol-benzene中国ponentsolventornon-protonpolarsolvent.分散剂为醇、醚、醇-苯混合溶剂或非质子...
(N1-tetrazole)-rapamycin, paclitaxel, docetaxel, estradiol, 17-beta-estradiol, nitric oxide donors, super oxide dismutases, super oxide dismutases mimics, 4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl (4-amino-TEMPO), dexamethasone, γ-hiridun, clobetasol, dexamethasone acetate, mometasone, ...
and administering an amount of the composition effective to achieve a certain quantity of the nucleic acid-based therapeutic to the cell. In another embodiment, the cell is a glioma cell. In another embodiment, the drug delivery system comprises poly(.beta.-L-malic acid) (PMLA) containing abou...
Giammona, G., “Polymeric Prodrugs alpha beta poly-hyroxyethyl-dl-aspartamide as macromolecular carrier for some non-steroidal anti-inflammatory agents”, Abstracts from Database BIOSIS Online, Biosciences Information Service, Philadelphia, PA, Original Publication from the International Journal of Pharmac...