Pol II is a complex enzyme, consisting of 12 subunits, of which the B1 subunit (UniProt/Swiss-Prot entry P24928) is the largest. Together with the second largest subunit, B1 forms the catalytic core of the RNA polymerase II transcription machinery. Anti-Pol II S2p Antibody is ideal for ...
ChIP was performed on sheared chromatin from 1 million HeLaS3 cells using 1 µg RNA Polymerase II S2p monoclonal antibody (Product # MA5-23510). The IP'd DNA was subsequently analyzed on a Genome Analyzer. The 36 bp tags were aligned to the human genome using the ELAND algor...
蛋白别名:3'-5' exoribonuclease; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; MGC75453; Pol II S2p; polyme...
Pol II occupancy as measured with the 8WG16 antibody was not markedly changed by KDAC inhibition (Figures 4A and 4B). Interestingly, S5p levels around the TSS remained unchanged, while beyond the ≥500-bp mark, S5p levels decreased below the level of control cells, mirroring enhanced K7ac ...
Consistent with this model, we observed that Pol II S2P signal increased through the body of the gene (Fig. 4a). S5P occupancy increased not only through the body of the gene but also showed a peak near the TSS and a depletion near the TES (Fig. 4a). Consistent with published ChIP-...
查看其他32个RNA pol II CTD抗体 货号PA5-17563 100 µL CNY4,211.00 查看价格 下单后预计有货时间 23-Jan-2025 数量 批量或定制请求 性能保障 说明书 实验方案 技术支持 抗体检测数据 (3) Application Created with Sketch. 图:1/3 Phospho-RNA pol II CTD (Ser2, Ser5) Antibody (PA5...
蛋白别名:3'-5' exoribonuclease; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; MGC75453; Pol II S2p;...
Phospho-RNA pol II CTD (Ser2, Ser5) Antibody (PA5-17563) in IHC (P) Immunohistochemistry was performed on paraffin-embedded human lung carcinoma tissue. To expose target proteins, antigen retrieval was performed by boiling tissue sections in 10mM sodium citrate buffer, pH 6.0 for 10 ...