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Quantification of intracellular bacteria in HeLa and HepG2 cells at 2 hours post-infection, at MOI 50 for HeLa and MOI 40 for HepG2. Averaged replicate values were normalized to inoculum concentration (CFU/mL at the time of infection) and the transformed data expressed as the percentage of...
1) apparently calculated expected values of the proposed lotteries, resulting in a majority of values (25 / 32) perfectly in sync with the expected values of the lotteries and a certain amount of large errors (7 / 32). Consequently, the PNP model indicates that most responses are perfect ...
Ethics declarations Competing interests The authors declare no competing financial interests. About this article Cite this article Buch, S., Stickel, F., Trépo, E.et al.A genome-wide association study confirmsPNPLA3and identifiesTM6SF2andMBOAT7as risk loci for alcohol-related cirrhosis.Nat Gene...
Odds ratios and P-values, adjusted for age, sex, body mass index (BMI) and the presence of type 2 diabetes mellitus, were calculated using multiple logistic regression analysis. Multiple linear regression analyses were performed to test the independent effect per allele of each SNP on biochemical...
Participants needed to have a magnetic resonance imaging-proton density fat fraction (MRI-PDFF) ≥7% and either a historical biopsy (up to 3 years old for F0-F2; 1 year old for F3), a historical magnetic resonance elastography scan with values between 2.55 kPa and 3.63 kPa, or a ...
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equilibrium, and the PH-W > 0.05 was regarded as consistent with the HWE.The sensitivity analysis was performed by assessing the change of combined ORs values after elimination of each individual study.The publication bias was evaluated using the Egger linear regression method and funnel chart...
Values for fibrosis ranged from 0.32 to 0.96, with an average value of 0.65 ± 0.18, close to the median value of the group (0.65), suggesting homogeneity of the series of values, which was confirmed by the results of Skewness and Kurtosis tests. Thus, statistically significant tests for co...
p-Values <0.05 were considered to be statistically significant. 5. Conclusions The main results of our study show that liver PNPLA3 expression is increased in NAFLD patients and is particularly associated to severity of steatosis. Moreover, PNPLA3 expression is correlated with the expression of ...