Author contributions Conceptualization, GF; formal analysis, ÁN and GF; funding acquisition, GF; investigation, ÁN, VG, and GF; project administration, AS and GF; resources, TM; supervision, AS and GF; validation, GF; writing—original draft, ÁN and GF; writ- ing—review & editing,...
The limitation of this study was a small sample size of individuals with simple steatosis; therefore, further studies would be necessary. Nevertheless, the approach used here of a combination of targeted resequencing and genotyping methods could be applied for the detailed investigation of other ...
To further our investigation of the role and importance of PNPLA3 gene polymorphisms in PLWH, we employed a unique cohort based in South Florida, the MASH (Miami Studies on HIV) cohort. HIV infection rates and mortality are among the highest in the nation [10]. This cohort accessed detailed...
Bempedoic acid (BemA) is an ATP-citrate lyase (ACLY) inhibitor used to treat hypercholesterolemia. We studied the anti-steatotic effect of BemA, and the mechanisms involved, in a model of fatty liver in female rats obtained through the administration of
While this study yields valuable insights, several critical limitations merit consideration. First, the study exclusively examined middle-aged and elderly populations, necessitating further investigation into the relationship betweenPNPLA3_rs738409, liver fat content, and metabolic disorders among adolescents ...
Overexpression of variant PNPLA3 gene at I148M position causes malignant transformation of hepatocytes via IL-6-JAK2/STAT3 pathway in low dose free fatty acid exposure: A laboratory investigation in vitro and in vivo. Am. J. Transl. Res. 2016, 8, 1319. [Google Scholar] Rafaqat, S.; Gl...
and T.K.; investigation, S.K., S.W. and T.K.; writing—original draft preparation, S.K., S.W. and Y.N.; writing—review and editing, S.K. and Y.N.; supervision, Y.N.; project administration, Y.N.; funding acquisition, S.K. and Y.N. All authors have read and agreed ...
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