1912年Delanoe夫妇研究了大鼠肺部的肺孢子菌感染并建立了动物模型,明确该虫种是一种新的病原体,将其命名为卡氏肺孢子虫(Pneumocystis carinii)。1942年Van der Meer和Brug发现人体中也存在肺孢子菌,1952年Vanek和Jirovec在营养不良儿童及新生儿的“浆细胞间质性肺...
The life cycle ofP. cariniiis simple and occurs within the alveoli of the lung. Four structurally distinguishable entities can be found in the infected lungs. They are trophozoites, precysts, cysts, and intracystic bodies. The structural features of these parasitic forms have been reviewed elsewher...
Pneumocystis cariniiLife cycleSexual reproductionMeiosisGametesis the most important opportunistic pathogen causing severe and often fatal infection in the immunocompromised host. Certain parts of the life cycle are still undetermined, including the existence and the fusion of gametes, the course of meiosis...
The life cycle, epidemiology, growth, metabolism, immunology and virulence of P. carinii are considered. Host defences against the disease, and its pathology, pathogenicity, clinical manifestations, diagnosis, treatment and prevention are described. 关键词: Human diseases Immunocompromised hosts Opportunist...
Pneumocystis carinii was originally thought to be a one-celled organism (a protozoan), but more recent research suggests that it is a fungus. Although its life cycle is known to have three stages, its method of reproduction is not yet completely understood. The complete name of the disease ...
因宿主的物种依赖性强,还改过名字:carinii → jirovecii 被小RNA核糖测序发现了是啤酒酵母的亲戚 04:54~09:00Transmission, life cycle and pathogenesis of pneumocystis jirovecii 肺孢子菌 传播方式 推测:pneumocystis jirovecii的肺...
Expression of P. carinii Cdc2 polypeptide in cdc2- mutant yeast and other cdc2-mutant organisms provides a for model for studying the life cycle of P. carinii and for identifying novel therapeutics.doi:US6015700 AAndrew H. LimperEdward B. LeofCharles F. ThomasMichael P. Gustafson...
carinii organisms, inocu- lated onto C E L cells, did not grow and CPE was not apparent. LIFE CYCLE Observations made of C E L cell cultures in Sykes-Moore chambers using phase contrast microscopy revealed that at 2 hr postinoculation, many cell-associated and unassociated orga- nisms ...
展开 关键词: Animals Humans Pneumocystis Pneumocystis carinii Trimethoprim-Sulfamethoxazole Combination Drug Resistance, Microbial Genotype Life Cycle Stages Pneumocystis jirovecii Anti-Infective Agents DOI: doi:http://dx.doi.org/ 被引量: 23 年份: 2004 收藏...
The complete life cycle of Pneumocystis carinii has not been defined, but accumulating evidence suggests that the mammalian host may acquire this organism ... CR Icenhour,SL Rebholz,MS Collins,... - 《Eukaryotic Cell》 被引量: 78发表: 2002年 Pneumocystis carinii in wildlife carinii infection....