We discuss also the effect of vaccines, including the 13-valent pneumococcal conjugate vaccine, on invasive pneumococcal diseases in children, particularly bacteraemia, pneumonia and meningitis, as well as on mucosal disease and carriage. In regions where immunization was implemented in young children,...
In five to 64 year olds the rates of pneumococcal disease targeted by the vaccine has more than halved and in people over 65 this reduction increased to 76 percent. Although all groups have seen fewer hospitalisations, the greatest reductions were seen in Māori and Pacific children and children...
Forty children and young adults with chronic renal diseases (including the idiopathic nephrotic syndrome, chronic renal failure, patients undergoing dialysis and after transplantation) were vaccinated with a 23-valent pneumococcal vaccine. The efficacy of the vaccine was evaluated by measuring antibody ...
Pneumococcal vaccine may be a future route to reduce antibiotic use and health care consumption in otitis-prone children. 展开 关键词: Conjugate vaccines PCV7 Recurrent acute otitis media Vaccination Ventilation tube treatment DOI: 10.1111/j.1651-2227.2011.02332.x 被引量: 58 ...
A conjugate vaccine containing the 7 serotypes responsible for about 90% of the invasive infections occuring in children in the United States has been shown to have a 97% protective efficacy against infections caused by vaccine serotypes. Pneumococcal conjugate vaccines are also protective, although ...
Failure of pneumococcal vaccine in children with sickle-cell disease The authors describe two children with sickle-cell anemia who contracted pneumococcal sepsis or meningitis (or both) after vaccination with 14-valent pneum... VI Ahonkhai,SH Landesman,SM Fikrig,... - 《New England Journal of ...
We found no evidence of a hidden circulation of vaccine-targeted serotypes, despite vaccine-serotypes still significantly contributing to invasive pneumococcal disease in unvaccinated individuals, supporting the presence of a substantialreservoir outside vaccinated children.Anne L. Wyllie...
Pneumococcal vaccine uptake among respondents who answered on their children’s behalf (n = 1064), overall and by NUTS statistical region; if the answer is no, the respondents are asked whether or not they would get their children vaccinated.Notes:Northwestern Italy includes the regions of ...
in preventing pneumonia and severe invasive infectious diseases. Therefore, the introduction of pneumococcal conjugate vaccines that are used in children is being discussed in adults, and PCV20 is significant because it is a vaccine that can completely replace the current polysaccharide vaccine. ...
1092 ANTIBODY RESPONSE TO PNEUMOCOCCAL VACCINE IN MALNOURISHED CHILDRENPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in vitro...