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Two condensates can be seen fusing over time (arrowheads). e, Co-condensation of Mal3:mCherry (200 nM), Tea2-Alexa647 (20 nM) and Tip1:GFP (150 nM) in the presence of 5% PEG-35k at the protein concentrations used in the MPET reconstitution assays. f, Mal3:GFP (200 nM...
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The vaccine targets the MICA and MICB (MICA/B) stress proteins expressed by many human cancers as a result of DNA damage2. MICA/B serve as ligands for the activating NKG2D receptor on T cells and NK cells, but tumours evade immune recognition by proteolytic MICA/B cleavage3,4. Vaccine-...
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