血小板输注指南GUIDELINESOFPLATELETTRANSFUSIONS 华西医院血液科李建军 血小板 •由骨髓中的巨核细胞产生。•生理作用：止血 维护血管内皮的完整性；粘附、聚集、释放形成血小板血栓止血；促凝功能。血小板的制备 •方法:手工法机采法浓缩血小板悬液（4.8x1010）单采血小板（2.5x1011）输注止血效果二者相似。•...
The benefits of pooled platelets or single donor platelets are similar; the two products can be used interchangeably. Single donor platelets from selected donors are preferred when histocompatible platelet transfusions (ie, HLA-A and HLA-B antigen matche...
Readers are referred to linked BSH guidelines on transfusion support in children and the use of viscoelastic haemostatic assays (VHAs).7, 8 Major haemorrhage is a clinical emergency that results in morbidity and mortality: practice guidance is important to reduce these risks. Delayed recognition of...
Guidelines for the use of platelet transfusions. British Journal of Haematology. 2017; 176(3):365-94.Estcourt LJ, Birchall J, Allard S, Bassey SJ, Hersey P, Kerr JP, Mumford AD, Stanworth SJ, Tinegate H. Guidelines for the use of platelet transfusions. Br J Haematol. 2017;176:365...
ABO-incompatible platelets are associated with increased transfusion reaction rates Transfusion, 60 (2020), pp. 285-293 CrossrefView in ScopusGoogle Scholar [10] Y. Chen, G. Li, M.L. Liu Microvesicles as emerging biomarkers and therapeutic targets in cardiometabolic diseases Dev Reprod Biol, 16...
2024, Biomarker Research Platelet transfusion enhances pro-aggregatory status shortly after coronary artery bypass grafting (CABG while modulating platelet pro-inflammatory state 1-week post-surgery 2024, Journal of Cellular and Molecular Medicine View all citing articles on ScopusData...
Severe thrombocytopenia should be corrected by prophylactic platelet transfusion prior to central venous catheter (CVC) insertion, according to national and international guidelines. Even though correction is thought to prevent bleeding complications, ev
Added safety measures coupled with the development and use of pathogen reduction technologies (PRT) significantly reduces the risk of transfusion-transmitted infections (TTIs) from blood products. Current approved PRTs utilize chemical and/or UV-light ba
We therefore lacked power to analyze the correlation between platelet dysfunction and clinical events; (iii) Most of the bleeding events reported in our study did not correspond to clinically identified bleeding but to transfusion of two or more units of PRBCs. Although this criterion is commonly ...
(TMU-JIRB N201802052). These clinical-grade PCs, initially intended for transfusion, were suspended in 100% plasma, were not leucoreduced, and were anticoagulated with a citrate–phosphate-dextrose solution. They were stored at 22 ± 2 °C under mild agitation, following standard licensed ...