This Review describes current evidence for the heterogeneity in platelet structure, age, and activation properties, with consequences for a diversity of platelet functions. Signalling processes of platelet populations involved in thrombus formation with ongoing coagulation are well understood. Genetic ...
Platelets — blood cells continuously produced from megakaryocytes mainly in the bone marrow — are implicated not only in haemostasis and arterial thrombosis, but also in other physiological and pathophysiological processes. This Review describes curren
Platelet biology and functions: new concepts and clinical perspectives 2019, Nature Reviews Cardiology Wound healing: A cellular perspective 2019, Physiological Reviews Targeting oxidative stress and mitochondrial dysfunction in the treatment of impaired wound healing: A systematic review 2018, Antioxidants Bl...
Platelet biology and functions: new concepts and clinical perspectives. Nat Rev Cardiol. 2019;16:166–79. https://doi.org/10.1038/s41569-018-0110-0. Article CAS Google Scholar Liao D, Zhou F, Luo L, Xu M, Wang H, Xia J, et al. Haematological characteristics and risk factors in the...
Platelet biology and functions: new concepts and clinical perspectives. Nat Rev Cardiol. 2019;16:166–79. PubMed Google Scholar Messora MR, Nagata MJH, Furlaneto FAC, Dornelles RCM, Bomfim SRM, Deliberador TM, et al. A standardized research protocol for platelet-rich plasma (PRP) preparation...
Although a growing number of studies suggest that microRNAs (miRNAs) play a relevant role in platelet biology, their implications in bleeding diatheses are starting to be investigated. Indeed, several studies have shown that alterations in the intracellular levels of highly expressed platelet miRNAs ...
Prostanoids are arachidonic acid metabolites and are generally accepted to play pivotal functions in amongst others inflammation, platelet aggregation, and... CL Bos,DJ Richel,T Ritsema,... - 《International Journal of Biochemistry & Cell Biology》 被引量: 659发表: 2004年 Platelet prostanoid recep...
The current understanding of platelet-derived growth factor (PDGF) physiological functions in vivo is discussed in the context of mouse development. In par... C Betsholtz - 《International Journal of Developmental Biology》 被引量: 69发表: 1995年 Platelet-Derived Growth Factor Signaling in the Lun...
The above stimulation was not altered by neomycin (200 μ m ), washing with EGTA (5 m m ) or by both incubating and washing with delipidized ... J Fermin,PJ Romero - 《Journal of Membrane Biology》 被引量: 3发表: 1994年 Aminoglycosides Induced Activation of Saponin-permeabilized Platele...
Its reception to other ligands and counter‐receptors in the blood stream also contribute to various processes of platelet biology that are still being discovered. While its basic composition and its link to congenital bleeding disorders were well documented and firmly established more than 25 years ...