Naturally occurring plasmids have medical importance given that they frequently code for virulence or antibiotic resistance. In many cases, plasmids impose a fitness cost to their hosts, meaning that the growth rate of plasmid-bearing cells is lower than that of plasmid-free cells. However, this ...
Plasmids and the spread of antibiotic resistanceThe evolution of multiple antibiotic resistanceThe clinical consequences of antibiotic resistanceMechanisms of antibiotic resistancePlasmids and bacterial virulencedoi:10.1002/9781444313741.ch6David K. Summers...
The plasmid is a key carrier of crucial genes in bacterial pathogens such as those related to acquired antimicrobial resistance (AMR) and virulence. It plays an important role in horizontal gene transfer (HGT), greatly shaping bacterial ecology and evolution [1]. Plasmids are transferred in bacter...
Carattoli A (2013) Plasmids and the spread of resistance. Int J Med Microbiol 303:298–304. https://doi.org/10.1016/j.ijmm.2013.02.001 Article MATH Google Scholar Casjens S, Palmer N, van Vugt R et al (2000) A bacterial genome in flux: the twelve linear and nine circular extrachro...
A Carattoli Plasmids and the spread of resistance Int J Med Microbiol, 303 (2013), pp. 298-304 10.1016/j.ijmm.2013.02.001 View in ScopusGoogle Scholar 48. AM Bolger, M Lohse, B Usadel Trimmomatic: a flexible trimmer for Illumina sequence data Bioinformatics, 30 (2014), pp. 2114-2120 ...
We investigated whether persisters can also promote the spread of resistance plasmids. In contrast to mutations, the transfer of resistance plasmids requires the co-occurrence of both a donor and a recipient bacterial strain. For our experiments, we chose the facultative intracellular entero-pathogen ...
Antibiotic resistance is common in bacteria that cause disease in man and animals and is usually determined by plasmids. The prevalence of such plasmids, and the range of drugs to which they confer resistance, have increased greatly in the past 25 yr. It has become clear from work in many...
The prevention of vancomycin-resistantEnterococcus faecium(VREfm) infections and transmissions poses a major challenge to hospitals. Vancomycin resistance can be plasmid encoded; however, as the analysis of plasmids is challenging, so far only a few reports have provided a detailed characterization of ...
Antibiotic resistance plasmids play important roles in resistance buildup and spread in soil and groundwater. However, very limited work has been reported in the literature to examine the transport behavior of free resistance plasmids in the environment. In this work, the transport of eight ...
Antibiotic resistance genes are often carried by plasmids, which spread intra- and inter genera bacterial populations, and also play a critical role in bacteria conferring phage resistance. However, it remains unknown about the influence of plasmids present in bacterial hosts on phage isolation and su...