Clinical indications for plasma protein assays: transthyretin (prealbumin) in inflammation and malnutrition. Clin Chem Lab Med 2007;45:419 -26.Myron JA, Merlini G, Sheldon J, et al. Clinical indications for plasma protein assays: transthyretin (prealbumin) in inflam- mation and malnutrition. Clin...
Two-hundred-and-ninety women were included in this study and donated a total of 312 blood samples; 198 in late pregnancy (~gw38) and 114 in the postpartum period (~w8). The plasma blood samples were analyzed for 92 immune system related protein markers using Proseek Multiplex Inflammation ...
We wanted to assess the role of beta2-glycoprotein I (β2GPI) a highly conserved plasma protein and its different biochemical forms in a mouse model of LPS systemic inflammation. Normal and β2GPI deficient mice were administered LPS through their veins and assessed for a range of inflammation...
antigen (PSA) in a middle-aged asymptomatic man may indicate undiagnosedprostate cancer. More From Britannica blood: Plasma Serum albumin, anotherproteinsynthesized by the liver,constitutesapproximately 60 percent of all of the plasma proteins. It is very important in maintainingosmotic pressurein the ...
Specifically, several circulating proteins are suggested to be biomarkers for inflammation, infection, and some systemic diseases [9,10,11]. With regard to malignancies, a number of cross-sectional studies have looked into the discrepancy in circulating protein levels between cancer sufferers and ...
solubility. The 3D structure of alpha-1-acid glycoprotein is shown inFig. 11.5. An alpha-1-acid glycoprotein is anacute phase protein, which means its concentration increases in response to conditions such as inflammation, infection, andinjuries(Tesseromatis et al., 2011; Huang and Ung, 2013...
Advanced oxidation protein products as a novel marker of oxidative stress in uremia Evidence suggests an imbalance between antioxidant and oxidant-generating systems resulting in oxidative stress in uremic patients. As plasma proteins are ... V Witko-Sarsat,M Friedlander,C Capeillère-Blandin,... ...
We explored the function annotation of each protein. Some of the genes coding for CHD-related proteins are linked to known CHD risk pathways via previous GWAS of lipids (APOB, LPA, ANGPTL3), coagulation pathways (GMP140), and systemic inflammation (sGP130, sICAM1) as shown in Fig.2. Man...
identified five protein modules reproducibly associated with HF risk in mid- and late-life, three of which are influenced bycis- andtrans-acting genetic variants. Additional systems-level analyses of HF-associated proteins provide further insight into relevant mechanistic and regulatory pathways for HF...
Some evidence suggests that chronic laminar inflammation might be associated with alterations in the endocrine and immune systems. We investigated this broad hypothesis by using DIGE to assess global differences in the plasma proteome between horses with chronic laminitis and controls. Results We ...