The 2-DE map of human plasma that resulted is recognizably the same as those produced later by many investigators: in contrast to cellular protein patterns, the plasma 2-DE pattern appears basically the same in everyone's hands perhaps due to the very high solubility of the proteins involved ...
Distribution of apoA-I between LpAI and LpAI:AII is consistent with a model of statistical partitioning regardless of sex and CETP genotype. The analysis also indicated that LpA-I accommodates on average 4 apoA-I molecules and has a clearance rate indistinguishable from LpAI:AII. Independent ...
The preterm lung is particularly vulnerable to ventilator-induced lung injury (VILI) as a result of mechanical ventilation. However the developmental and pathological cellular mechanisms influencing the changing patterns of VILI have not been comprehensi
6c, this pre-cross-linking induced by APPJ treatment is beneficial to the material since the elastic modulus obtained after photo-cross-linking is twice as higher than that measured on untreated hydrogels after the same irradiation time. The counterpart to this higher extent of cross-linking is ...
The values obtained by cross-validation methods were somewhat lower and would correspond to a “less accurate” test. This is not strange as it its well known that the establishment and maintenance of pregnancy depends upon several genetic and environmental factors. Previous reports in the human ...
Blood phosphorylated tau (p-tau) forms are promising Alzheimer’s disease (AD) biomarkers, but validation in matrices other than ethylenediaminetetraacetic acid (EDTA) plasma is limited. Firstly, we assessed the diagnostic potential of p-tau231 and p-tau181 in paired plasma and serum samples. Se...
Plasma amyloid-β (Aβ) may facilitate identification of individuals with brain amyloidosis. Gut microbial dysbiosis in Alzheimer’s disease (AD) is increasingly being recognized. However, knowledge about alterations of gut microbiota in preclinical AD,
is clear from the setting of the experiments that there is some variation in the real point in time when the blood probe has been taken: the true time when the measurement value has been obtained might be shortly before or after the intended time, and this true measurement time is not ...
Considering that a substantial percentage of circulating lipids are transported by lipoproteins synthesised in the liver, it is plausible that hepatopathy could contribute to plasma lipidome changes. The treatments with short-term prednisolone and long-term tetracosactide had distinct effects on the dog...
To evaluate the sensitivity of both docetaxel and the IS, different solvent types and additives in various concentrations and ratios were tested. Better peak shapes and optimal sensitivity were obtained with the addition of 0.1% formic acid and acetonitrile as the organic solvents. Using the gradient...