Plasma is referred to as the 4th state of matter, and it consists of electrons, ions and reactive species. The medical term “plasma” was coined by Irving Langmuir because “plasma” in physics is analogous to the plasma that is ionic liquids in medicine21. However, the use of plasma in...
We use the term plasma preferentially to refer to the soluble proteome of the blood because it is the parent mixture and because there may be persuasive reasons to avoid an in vitro proteolysis process (which may unexpectedly alter some proteins) as part of the preferred sample acquisition ...
II. Plasma levels of the drug, some of its metabolites and prolactin in patients receiving long-term... Plasma levels of chlorpromazine (CPZ), 3 of its metabolites and prolacin were measured repeatedly in 18 chronic schizophrenic patients. The patients were s... T Kolakowska,DH Wiles,MG ...
Hypoglycemia in newborn infants of normal and diabetic mothers. Term infants, 193 in all, from normal mothers were compared with 38 from diabetic mothers. Infants nursed in incubators, the practice for infants from diab... JW Farquhar,TE Isles - South African medical journal = Suid-Afrikaanse ...
The nearest and long-term results of vagotomy and resection of the stomach are shown in comparison. Totally, organ-preserving interventions give more promising results than resection of the stomach especially by the Billroth-II method. After vagotomy, however, recurrent disease was observed in 8,4...
We used the implementation in the R glmnet package. The biomarkers selected from the Lasso method were then refitted in the Cox proportional hazards regression models. We evaluated effect modification by race and sex by testing the statistical significance of a multiplicative interaction term in ...
We investigated the predictive abilities of ProRS across different time windows, for most endpoints, the ProRS achieved the highest area under the ROC curve (AUC) when forecasting outcomes happening within 5 years, suggesting a pivotal role of plasma proteomics in detecting near-term risks. For ...
Elevated plasma vitamin B12 levels (cobalamin, Cbl) are associated with increased short-term cancer risk among patients referred for this laboratory measurement. We aimed to assess prognosis in cancer patients with elevated plasma Cbl. We conducted a population-based cohort study using data from Danis...
the analysis of cfDNA in blood and urine has already promised utility in the context of early bladder cancer diagnosis and detection of metastatic relapse following cystectomy14,31. Therefore, considering our hypothesis-generating study, we posit that cfDNA profiling is poised for near-term clinical ...
The studies were approved by local ethical committees in the respective countries. For C1: Ottawa Health Science Network Research Ethics Board and for C2: the Medical Ethics Committee of the University Hospital Maastricht and Maastricht University, the Netherlands; the Committees on Biomedical Research ...