Bone marrow biopsyimmunocytochemistrylight chain immunoglobulinplasma cell dyscrasiatumour quantitationDirect measurement of monoclonal plasma cell mass in bone marrow biopsies may be a useful parameter to establish in plasma cell dyscrasia. In this study monoclonal plasma cells/mm[sup 2] in light ...
Normal and reactive plasma cells (PC) are easy to ascertain on human bone marrow films, due to their small mature-appearing nucleus and large cytoplasm, the latter usually deep blue after Giemsa staining. Cytoplasm is filled with long strands of rough endoplasmic reticulum and one large Golgi ap...
Related to Plasma cells:Macrophages,Histiocytes,Memory cells n. Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, and lymph nodes. Also calledplasmacyte. ...
Solitaryplasmacytomasare composed of plasma cells, which on biopsy are histologically identical to those seen in MM. Solitary plasmacytomas most frequently occur in bone (SPB), but can also be found insoft tissues.22–24SBP is characterized by a biopsy-proven clone of plasma cells, bone survey...
intbut at much reduced amounts on Blimp1hiplasma cells. Finally, using Blimp1 as a marker of plasma cells revealed a preponderance of Blimp1hiplasma cells in the bone marrow, an equal distribution of Blimp1intand Blimp1hiin the spleen, and an excess of Blimp1intin the blood, all ...
A bone marrow biopsy revealed 40% plasma cells with κ light chain restriction. Thus, she was considered to have MM. A renal biopsy revealed neoplastic plasma cell infiltration within the kidney, moderate interstitial fibrosis, tubular atrophy, and punctate, electron-dense material along the ...
Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of protective antibodies1–7. Individuals who have recovered from COVID-19 have a substantially lower risk of reinfection with SARS-CoV-28–10. Nonetheless, it has been rep
A bone marrow biopsy revealed 40% plasma cells with κ light chain restriction. Thus, she was considered to have MM. A renal biopsy revealed neoplastic plasma cell infiltration within the kidney, moderate interstitial fibrosis, tubular atrophy, and punctate, electron-dense material along the ...
@gardenturtle: There is a condition called plasma cell myeloma (also known as multiple myeloma, Kahler disease, and myelomatosis). It is a type of cancer that begins in the plasma cells. It occurs when abnormal plasma cells multiply uncontrollably in the bone marrow. ...
The case described presented with pyrexia, enlargement of the spleen, and profound depression of both red and white cells. The bone marrow was markedly hypoplastic. There was no clinical or radiological evidence of disseminated tuberculosis, and no glands were available for biopsy. Culture and guine...