Related to plasma cell leukemia:plasma cell myeloma leu·ke·mi·a (lo͞o-kē′mē-ə) n. Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs, usually accompanied by anemia, impaired blood clotting, and enlar...
A total of 128 cases of plasma cell leukemia were collected, and 73 of them (57%) were classified as primary (male/female 43/30).Results: Sixty-four patients had at least 1 sign of end-organ damage and 10 had extramedullary localization. One patient died early; of the remaining patients...
Plasma cell leukemia: Typically aggressive with short survival < 1 year > 2 x 109/L or 20% of the leukocyte count on differential are monoclonal plasma cells Primary plasma cell leukemia (0.6% of myeloma) or develop as a late stage transformation (secondary) (Curr Oncol Rep 2019;21:8) Us...
Leukemia (leukapheresis) (for acute debulking only) including mantle cell lymphoma (mantle cell leukemia) if white blood cells count is greater than 100,000/µL; or Myasthenia gravis, in persons with any of the following: Acute, short-term benefit is critical because of a sudden worsening of...
Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell proliferative disorder with a very poor prognosis and with distinct biologic, clinical, and laboratory features. Compared with multiple myeloma, pPCL presents more often with extramedullary involvement, anemia, thrombocytopenia, hype...
Similar to esophageal cancer, STMN1 is highly expressed in various cancers, including leukemia, breast, prostate and lung cancer, and is a promising target for cancer therapy26,27. There is some evidence that it may have a prognostic significance in the early-stage gastric cancer. For example,...
Early studies established that certain lipids were lower in acute myeloid leukemia (AML) cells than normal leukocytes. Because lipids are now known to play an important role in cell signaling and regulation of homeostasis, and are often perturbed in malignancies, we undertook a comprehensive lipidomi...
Convalescent plasma to aid in recovery of COVID-19 pneumonia in a child with acute lymphoblastic leukemia. Transfus Apher Sci. 2021;60(1):102956.Google Scholar 144. Spinicci M, Mazzoni A, Borchi B, et al. AIDS patient with severe T cell depletion achieved control but not...
et al. Increased integrity of circulating cell-free DNA in plasma of patients with acute leukemia. Clin. Chem. Lab. Med. 48, 1651–1656 (2010). CAS PubMed Google Scholar Yi, X. et al. The feasibility of using mutation detection in ctDNA to assess tumor dynamics. Int. J. Cancer ...
Primary plasma cell leukemia (pPCL) is a rare and aggressive form of multiple myeloma (MM) that is characterized by the presence of ≥20% circulating plasma cells. Overall survival remains poor despite advances of anti-MM therapy. The disease biology as well as molecular mechanisms that distingui...