Plasma cell dyscrasia is a result of an abnormal clonal proliferation of plasma cells. These cells arise from B cells in the bone marrow and produce immunoglobulins. Multiple myeloma is a type of plasma cell dyscrasia that commonly presents with symptoms secondary to hypercalcemia, hyperviscosity...
plasma cell dyscrasia A lymphoproliferative disorder characterized by monoclonal proliferation of plasma cells, with clinical behavior ranging from innocuous extramedullary plasmacytomas to premalignant solitary plasmacytoma of bone to myeloma. CfMonoclonal gammopathy of undetermined significance,Myeloma. ...
Since last few years plasma cell dyscrasias have been in the hit list of research especially pertaining to its therapy and pathophysiology. India has taken a great leap as far as research in plasma...doi:10.1007/s12288-019-01075-zChatterjee, Tathagat...
Plasma cell dyscrasiais a condition characterized by abnormal synthesis of Ig molecules or subunits. Multiple myeloma (MM) is the most advanced form of plasma cell dyscrasia, comprising 10% of hematological cancers.123MM is defined by the presence of 10% or more monoclonal plasma cells in bon...
Plasma-Cell Dyscrasia and Peripheral Neuropathy with a Monoclonal Antibody to Peripheral-Nerve Myelin We reviewed a series of 109 reported Japanese cases of "plasma cell dyscrasia with polyneuropathy and endocrine disorder." This syndrome shows 1) polyneuro... Latov,Norman,Sherman,... - 《New...
Possibility that this syndrome and osteosclerotic myeloma (polyneuropathy and bone sclerotic bone lesions) may both be manifestations of plasma-cell dyscrasia; Details of a study which concludes that plasma-cell dyscrasia with polyneuropathy is a rare multisystem disease that often presents with osteo...
In conclusion, TEMPI syndrome should be considered when erythrocytosis and plasma cell dyscrasia coexist. The bone marrow findings, although nonspecific, differ significantly from polycythemia vera. Peculiar clinical and laboratorial findings of TEMPI, including elevated erythropoietin and normal vascular ...
Plasma cell dyscrasia associated with the production of incomplete IgG lambda molecules, gamma heavy chains, and free lambda chains containing carbohydrate: description of the first case. Blood. 1974;43:505–26.Isobe, T., Osserman, E. F. Plasma-cell dyscrasia associated with the production of...
Biosynthesis of J-chain in human lymphoid cells producing immunoglobulins of various isotypes Mol Immunol (1983) PL Haber et al. J-chain expression in human cells producing IgG subclasses Cell Immunol (1985) J-P Bouvet et al. IgM reassociation in the absence of J-chain Immunol Lett (1987) ...
Biological and clinical relevance of miRNA expression signatures in primary plasma cell leukemia. Purpose: Primary plasma cell leukemia (pPCL) is a rare and very aggressive form of plasma cell dyscrasia. To date, no information on microRNA (miRNA) expre... M Lionetti,Pelligrino Musto,MTD ...