The patient presented with symptoms such as decreased appetite, fatigue, myalgia, fever, and back pain. Initial evaluation raised concerns for a plasma cell disorder, but further testing confirmed a diagnosis of dengue with transient plasmacytosis. Plasmacytosis is rare and is typically associated ...
of multiple myeloma and its diagnosis, monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, plasmacytoma, plasma cell leukemia, the clinical presentation of multiple myeloma bone disease, anemia, renal impairment, hypercalcemia, and neurologic symptoms associated with multiple myeloma...
It includes a spectrum of plasma cell disorders ranging from monoclonal gammopathy of unknown significance (MGUS), a relatively benign condition to smoldering multiple myeloma (SMM), as well as the symptomatic malignant disorder MM, and its more aggressive form, plasma cell leukemia with circu- ...
The invention relates to novel biological markers for plasma cell disorders, such as multiple myeloma, and in particular to the use of microRNAs as diagnostic and prognostic markers
related to the underlying plasma cell disorder, includinghypercalcemia(C), renal failure (R), anemia (A), andbone lesions(B), commonly named the CRAB symptoms acronymically. Smoldering or asymptomatic MM is present when the same degree of paraprotein in serum and plasmacell infiltrationof the ...
While the psychiatric symptoms of schizophrenia can be managed by current antipsychotic medications, there is room for improvement in the management of other aspects of the disorder, such as the cognitive deficits and significantly reduced lifespan seen in persons with schizophrenia. Despite the presence...
In classical terms, a plasma cell is a terminally differentiated B lymphocyte, and a myeloma cell is its neoplastically transformed progeny. These are simplistic definitions, for plasma cell disorders (PCDs) are a complex group comprising a diverse spect
Deciphering the Impact of miR-92a-3p on Controlling BCL11A Gene Expression and Its Implication in Easing Thalassemia Symptoms Thalassemia, a prevalent genetic disorder, is characterized by a point mutation affecting the globin gene expression. One manifestation of this disorder,尾... MMS Al-Khafaji,...
The recent development of a reproducible, live cell-based assay for MOG-IgG, has improved the ability to identify and study this disease. Based on contemporary studies, it has become increasingly evident that MOG-AD is distinct from MS and aquaporin-4-positive NMO spectrum disorder with ...
borderline personality disorder.48 Higher serum levels of HGF have also been found in those patients with panic disorder who best responded to antidepressant medication.49 To this literature, we add our finding of an increase in plasma HGF levels with increasing depressive symptoms in older adults....