An UpToDate review on “Clinical manifestations, diagnosis, treatment, and prevention of babesiosis” (Gelfand and Vannier, 2012) states that “Partial or complete red cell exchange transfusion is appropriate for patients with high-grade parasitemia (≥10 percent), severe anemia (hemoglobin ≤10 g/...
2 MGUS is defined as the presence of a serum monoclonal protein <3.0 g/dL, <10% clonal plasma cells in the bone marrow, and the absence of end-organ damage related to the disorder. The diagnostic criteria for plasma cell disorders is depicted in Table 2.2 In a large study, the ...
Unlike the CIS-R, the PLIKSi does not provide ICD-10-defined diagnoses. However, individuals who fulfilled the definition of psychotic disorder in our study would also likely meet ICD criteria since they were experiencing regular psychotic symptoms associated with severe distress or impairment. The ...
Congenital heart disease (CHD) is the most common congenital disorder diagnosed in newborns. Although lots of related studies have been published, yet the pathogenesis has not been fully elucidated. A growing body of evidence indicates perturbations of the gut microbiota may contribute in a significan...
Cardiac amyloid: Approximately 10% of patients with MM can have concomitant light chain (AL) amyloidosis, the most common type of systemic amyloidosis associated with plasma cell dyscrasias; often this association is missed at the time of MM diagnosis. In amyloidosis, heart involvement is seen in...
Previous studies have revealed that soluble OAβ in the brain were involved in the early stages of AD pathology and predate classic fibrillar amyloid plaque deposition, neuronal cell loss, and memory impairment [28]. Other previous studies have reported elevations in OAβ levels in CSF and brain...
Cell Mol Bio. 1997;43(7):1115–22. CAS Google Scholar Atkinson JH, Heaton RK, Patterson TL, et al. Two-year prospective study of major depressive disorder in HIV-infected men. J Affect Disord. 2008;108(3):225–34. Article PubMed Google Scholar Bing EG, Burnam MA, Longshore D, ...
Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics. Nature Genet. 2022;54(10):1479–1492. doi:10.1038/s41588-022-01187-9 (Open in a new window)PubMed(Open in a new window)Google Scholar...
Additional QC measures for almost all analytes were employed specifically for the ADNI plasma analysis by testing blank human plasmas spiked with extracts of cell cultures expressing the individual analytes. Samples from the total ADNI plasma cohort were run on 15 plates. APOE genotyping. DNA was ...
We did not complete the analysis of the three-way interaction between high tHcy, aspirin and B-vitamin because of a very large s.e.(that is, 5.39) of the OR caused by the presence of only three persons in the cell associated with depression. Discussion The results of this study ...