HRPs are defined as having two or more characteristics on the CCTA associated with a higher likelihood of having an acute coronary syndrome (ACS) [6]. These characteristics include low attenuation plaque, spotty calcification, positive remodeling, and the napkin ring sign. In patients with stable ...
, Quantification of the density of diffuse plaques (defined as above) expressed as a fraction of total plaques in the cortex of mice of the indicated genotypes at 12 mo. Data represent diffuse plaques quantified from N = 4-5 sections from n = 6 mice per group. (...
Amyloid can be defined as an aggregation or deposit of proteins. The characteristics of amyloids include their fibril structure and their inability to be solubilized by normal biological methods of recycling proteins. Fibrils are linear unbranched fibers in form, made up of smaller subunits. Each fi...
However, periprocedural myocardial infarction (PMI), which is defined as a significant elevation of troponin within 48 h after PCI accompanied by clinical features of myocardial ischemia (MI) [1], is not uncommon. PMI has emerged as a frequent and severe complication of PCI, with incidences ...
(Sigma-Aldrich). The necrotic core was defined as the acellular, debris-rich lesion area as percentage of total plaque area. Corresponding sections on separate slides were stained for monocyte/macrophage content with a MOMA-2 antibody (1:1000, AbD Serotec) followed by a biotinylated goat anti-...
On the scan, health care professionals may be able to see well-defined areas of thickening. These areas are often described as nodular, linear structures on the surface of the lung tissue. Some researchers have even noted they resemble a basket weave. ...
8, 9, 10 The stage in plaque development at which neovascularization occurs has not been precisely defined. Neovessels have been observed in early fatty streaks and appear to become more prominent and numerous as the lesion advances.11 The importance of neovessel formation for growth of ...
Plaques that are most vulnerable for rupture are thin-capped fibroatheromas, which are defined by hallmarks of a thin fibrous cap, a large lipid-rich necrotic core, and inflammatory infiltrate. These plaques are non-obstructive to moderately obstructive, thus asymptomatic and unidentifiable with ...
Results The presence of CPs was also comparable across the various IJD [RA, n= 76 (77.6%), AS: 36 (85.7%), PsA 15 (88.2%), p=0.38]. In logistic regression analyses CPs was significantly associated with CA (Table) independent of the 3 CV risk calculators: SCORE, Framingham and ...
Type 4 atherosclerotic plaques are lesions characterized by a dense accumulation of extracellular lipids, which act as a lipid core and occupy an extensive, over 85%, but well-defined intimal area. The degranulation of the intima and accumulation of fibrous tissue can cause lesion defects, rupture...