Figure 1. Domain architecture and proposed classification of ubiquitin regulatory X (UBX) domain-containing proteins. Folded protein domains are shown boxed with domain names. The first two letters of the protein name indicate the species: At, Arabidopsis thaliana; Ce, Caenorhabditis elegans; Hs, Ho...
Functional characterization of the plant ubiquitin regulatory X (UBX) domain-containing protein AtPUX7 in Arabidopsis thaliana[J] . Jean-Luc Gallois,Jan Drouaud,Alain Lécureuil,Anouchka Guyon-Debast,Sandrine Bonhomme,Philippe Guerche.Gene . 2013 (2)...
Here we show that one member of the plant UBX domain-containing protein family (PUX), PUX1, regulates AtCDC48 by inhibiting its ATPase activity and by promoting the disassembly of the active hexamer. Phenotypic analysis of pux1 plants revealed that the loss of PUX1 accelerated the growth of...
The ubiquitin regulatory X (UBX)-containing protein, PUX1, functions to regulate the hexameric structure and ATPase activity of AtCDC48. To characterize the biochemical mechanism of PUX1 action on AtCDC48, we have defined domains of both PUX1 and AtCDC48 that are critical for interaction and...
Protein conservation analysis was performed with blastp (https://blast.ncbi.nlm.nih.gov). All proteins and domains are drawn in approximate scale. The color codes are described in Fig. 1. Gray boxes indicate transmembrane domains. The localization of transmembrane domain containing proteins is ...
This interaction stabilises LDs by preventing their degradation, which would otherwise be mediated by the PUX10 protein containing a UBX domain. As a result, LD stabilisation maintains levels of C18 polyunsaturated fatty acids (PUFAs), which are critical for viral replication and systemic spread (...
G-box protein MOB: MOB kinase activator-like UBX2: Ubiquitin regulatory X domain-containing protein 2 SWI/SNF: SWItch/sucrose non-fermentable EIN3: EIN3-like (EIL) transcription factor family FREE1: Free domain protein required for endosomal sorting 1 ...
The AGAMOUS-like 20 MADS domain protein integrates floral inductive pathways in Arabidopsis. Genes Dev. 14, 2366–2376 (2000). A gain-of-function allele of SOC1 was identified as a suppressor of the late-flowering phenotype of frigida (fri ) mutants. SOC1 is regulated by all three ...
Proteins containing a ubiquitin regulatory X (UBX) domain are cofactors of Cell Division Cycle 48 (CDC48) and function in protein quality control. However, whether and how UBX-containing proteins participate in host–microbe interactions remain unclear. Here we show that MoNLE1, an effector from ...
Y. Protein domain–domain interactions and requirements for the negative regulation of Arabidopsis CDC48/p97 by the plant ubiquitin regulatory X (UBX) domain-containing protein, PUX1. J. Biol. Chem. 282, 5217–5224 (2007). Article CAS Google Scholar Moreau, M. et al. Mutations in the ...