If the placenta is not functioning properly, it can be the limiting factor not only for fetal nutrition, but also for the maternal–fetal exchange of physiological constituents as well as waste products that may represent a pathologic risk to the fetus. Some drugs ingested by the mother may ...
4) has an extraplacental lobe that is not contiguous with the main placental body. This condition may be associated with retained placental tissue or may predispose to rupture of the bridging vessels during delivery. Both these conditions may lead to subsequent postpartum hemorrhage.11-13 In a ...
between any of the three placental tissues and the average of the 16 non-placental tissues as similarly defined in another study [11]; and (2) placenta-specific genes, defined as genes whose RNA-Seq reads were only detected in the placenta but not in any of the 16 non-placental tissues....
Despite such interesting anecdotal examples, the global patterns of AS of human genes have not been examined systematically in the placenta. In this study, we used high-throughput RNA-Seq to conduct a genome-wide analysis of the normal placental transcriptome. RNA-Seq is a powerful technology ...
cancerous cells Keiichi Hatakeyama1*†, Yorikane Fukuda1,4†, Keiichi Ohshima1, Masanori Terashima2, Ken Yamaguchi3 and Tohru Mochizuki1 Abstract Background: Alternative splicing of pre-mRNA transcripts not only plays a role in normal molecular processes but is also associated with cancer ...
between any of the three placental tissues and the average of the 16 non-placental tissues as similarly defined in another study [11]; and (2) placenta-specific genes, defined as genes whose RNA-Seq reads were only detected in the placenta but not in any of the 16 non-placental tissues....
These effects do not just act in low birth weight babies but have been shown to occur within the normal range of birth weight. It is thought that fetal adaptations to an impaired intra-uterine environment may enhance survival in early life but have deleterious effects in later life.Experimental...
"We found that in the placenta, mitochondria have a remarkable ability to adapt and compensate for environmental impacts such as when women are living in low oxygen areas athigh altitudeand not eating enough of a healthy diet during pregnancy." ...
To date, the expression profile of lncRNA in human term placenta has not been fully established. This study was conducted to characterize the lncRNA expression profile in human term placenta and to verify whether there are differences in the transcriptomic profile between the sex of the fetus ...
In their study, the researchers looked for the amount of maternal DNA in the babies' umbilical cord blood. This is representative of the level of maternal microchimerism the children had at the moment they were born, Harrington said, although it's not known how long that level may persist ...