Results A total of 96 trials met the eligibility criteria; 59 trials had no run-in (which included those with a screening or withdrawal period), 37 trials had a placebo run-in, and no trials had a drug run-in. The magnitude of the effect estimates for all outcomes did not importantly ...
求翻译:During the single-blind placebo spray run-in period, patients had to have a minimum reflective TNSS of 36 of a possible 72 points on 3 of the 4 days before randomization into the double-blind treatment phase of the study是什么意思?待解决 悬赏分:1 - 离问题结束还有 During the singl...
aDuring the single-blind placebo spray run-in period, patients had to have a minimum reflective TNSS of 36 of a possible 72 points on 3 of the 4 days before randomization into the double-blind treatment phase of the study 在唯一瞎的安慰剂浪花磨合期,患者在3必须在随机化之前有极小的反射性...
PATIENTS: Ninety-seven patients with orthostatic hypotension were randomized in a 4-week, double-blinded, placebo-controlled study with a 1-week placebo run-in period. Patients ranged in age from 22 to 86 years (mean: 61 years). METHODS: After a 1-week run-in phase, either placebo or ...
The trial, which included a 1-month placebo run-in period, showed that both placebo and nicergoline were associated with some degree of improvement. The effect of nicergoline, however, was significantly greater and more sustained, steadily increasing with time. In particular, the difference between...
Does a Placebo Run-In or a Placebo Treatment Cell Affect the Efficacy of Antidepressant Medications? During the last decade, there has been an increasing use of a placebo run-in period prior to randomization to active treatments, or placebo in randomized c......
This model demonstrated that a greater frequency of run-in heartburn was a significant negative predictor of heartburn resolution during the follow-up period, with an adjusted odds ratio (OR) of 0.68 (95% confidence interval [CI]: 0.61–0.77) for each additional 1-day increase in heartburn ...
The SEED trial design was shown in the Extended Data Fig. 1, in which it showed the process of T2D patients completing the SEED study. Selected drug naive T2D patients entered into a 4 week single-blinded placebo run-in period followed by a randomization into a 24-week double blinded place...
This was a double-blind, randomized, placebo-controlled multicenter, titration-to-effect study of eprosartan in patients > or =60 years of age with isolated systolic hypertension. The study consisted of a 3 to 5-week placebo run-in period, a 13-week double-blind treatment period (6-week ti...
The effect of PF-05089771, a selective, peripherally restricted Nav1.7 sodium channel blocker on pain due diabetic peripheral neuropathy was investigated in a randomised, placebo and active-controlled parallel group clinical trial (NCT02215252). A 1-week placebo-run in period was followed by a 4-...