Evidence for involvement of the PKC-alpha isoform in myogenic contractions of the coronary microcirculation. Am J Physiol Heart Circ Physiol 2000 September;279(3):H916-H923. [PubMed: 10993750]Dessy C, Matsuda N, Hulvershorn J, Sougnez CL, Sellke FW, and Morgan KG. Evidence for involvement...
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nan Atypical GTF2F1 Q6IBK5 Col4A3BP COL4A3BP Collagen type IV alpha-3-binding protein Atypical Col4A3BP Q9Y5P4 BLVRA BLVRA Biliverdin reductase A Atypical BLVRA P53004 BAZ1A BAZ1A Bromodomain adjacent to zinc finger domain protein 1A Atypical BAZ Q9NRL2 BAZ1B BAZ1B Tyrosine-protein kinas...
[3] Koya D.Dual protein kinase C alpha and beta inhibitors and diabetic;kidney disease:a revisited therapeutic;target for future clinical trials[J].Diabet Investig,2014,5(2):47-48. [4] Steinberg SF,Goldberg M.Rybin V0.Protein kinase C isoform diversity in the heart[J].J Mol Cell Cardio...
Protein kinase C alpha (PKC alpha) acts upstream of PKC theta to activate IkappaB kinase and NFkappaB in T lymphocytes. Mol. Cell. Biol. 2003; 23; 7068-7081.Trushin S A,Pennington K N. Protein kinase C alpha (PKCalpha) acts upstream of PKC theta to activa...
This upregulation, demonstrated for both synaptic and extrasynaptic AMPARs, depends on the protein kinase C alpha (PKCα) activation; hence, spinal PKC inhibition has alleviated peripheral nociceptive hypersensitivity. However, whether targeting the spinal PKCα would alleviate both pain development and...
PKCα、PCNA、GFAP、EGFR在脑胶质瘤中的表达及临床意义 【摘要】 目的 探讨蛋白激酶Cα、增殖细胞核抗原、胶质纤维酸性蛋白、表皮生长因子受体的表达、相互关系及其意义。方法 采用免疫组织化学法,检测55例脑胶质瘤标本中PKCα、PCNA、GFAP和EGFR的表达。结果 PKCα、PCNA和EGFR的表达随胶质瘤病理分级的增加而增高,而...
pkc-1 isoform activation is required for egf-induced nf-b inactivation and ib stabilization and protection of f-actin assembly and barrier function in ente... 2004. PKC- beta1 isoform activation is required for EGF-induced NF-kappaB inactivation and IkappaBalpha stabilization and protection of ...
We first excluded the possible upregula- tion of another -cell PKC isoform capable of promoting insulin secretion. Although we did find a small but signif- icant increase in PKC␣—a conventional PKC—in lipid- cultured PKCεKO islets, this is unlikely to be of function...
Here we identified the PKCα isoform as a target for E2-induced signal transduction in this cell line. A time course for the effect of E2 on PKCα activation was studied in RL95-2 and HEC-1A cell lines by Western blotting analysis using an antibody directed against the PKCα Ser657 ...