Zhao X, Liu F, Jin H, Li R, Wang Y, Zhang W, Wang H, Chen W. 2017. Involvement of PKCalpha and ERK1/2 signaling pathways in EGCG's protection against stress-induced neural injuries in Wistar rats. Neuroscience. 346:226-237.
family of phospholipid-dependent serine/threonine kinase and involves in various cellular processes such as cell proliferation, apoptosis, invasion and migration. previous studies have shown that activation of pkc alpha is required for tpa-induced erk signaling to trigger gene expressions of p15(ink4b)...
“non-epidemic KS” subtype. These customers tend to be called healthy, middle-aged, HIV-negative MSM with reduced extremity lesions. This descriptive report provides an updated view of KS threat elements and effects to enhance recognition and treatment in dermatology. Intensity-modulated helical ...
and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of pro...
Stable transfection of protein kinase C alpha cDNA in hormone-dependent breast cancer cell lines. Br J Cancer 2000; 83: 782–791. Article CAS PubMed PubMed Central Google Scholar Tonetti DA, Morrow M, Kidwai N, Gupta A, Badve S . Elevated protein kinase C alpha expression may be ...
E2F-1, a transcription factor implicated in the activation of genes required for S phase such as DNA pol alpha, is regulated by interactions with Rb and by... CM Simbulan-Rosenthal,DS Rosenthal,RB Luo,... - 《Oncogene》 被引量: 81发表: 0年 加载更多来源...
Integrin alphaMbeta2 clustering triggers phosphorylation and activation of protein kinase C delta that regulates transcription factor Foxp1 expression in monocytes J. Immunol., 184 (2010), pp. 3697-3709 CrossrefView in ScopusGoogle Scholar 50 S.O. Rahaman, D.J. Lennon, M. Febbraio, E.A. ...
alpha-6 AGC RSK Q9UK32 SGK2 SGK2 Serine/threonine-protein kinase Sgk2 AGC SGK Q9HBY8 SGK3 SGK3 Serine/threonine-protein kinase Sgk3 AGC SGK Q96BR1 GPRK7 GRK7 G protein-coupled receptor kinase 7 AGC GRK Q8WTQ7 YANK1 STK32A Serine/threonine-protein kinase 32A AGC YANK Q8WU08 CRIK CIT...
In PKCα-overexpressing T47D xenografts, an orally active γ-secretase inhibitor at clinically relevant doses significantly decreased estrogen-independent tumor growth, alone and in combination with TAM. In conclusion, PKCα overexpression induces Notch-4 through AP-1. Notch-4 promotes estrogen-...
alpha-6 AGC RSK Q9UK32 SGK2 SGK2 Serine/threonine-protein kinase Sgk2 AGC SGK Q9HBY8 SGK3 SGK3 Serine/threonine-protein kinase Sgk3 AGC SGK Q96BR1 GPRK7 GRK7 G protein-coupled receptor kinase 7 AGC GRK Q8WTQ7 YANK1 STK32A Serine/threonine-protein kinase 32A AGC YANK Q8WU08 CRIK CIT...