Sometimes, it is essential to know the accurate strength (p K a values) of the acids/bases to work with, but sometimes just acidity/basicity order is enough. We often receive requests to measure p K a values of different substances in different solvents for answering questions like "what ...
The concepts of acidity and pKa values often occupy a privileged place in the undergraduate organic chemistry curriculum. However, by neglecting the relationship between solvent and acidity, many students come to understand acidity as a fixed property of a molecule, invariant regardless of reaction ...
Robert J.Ouellette,J. DavidRawn, inPrinciples of Organic Chemistry, 2015 Basicity of Amines 12.19 The pKavalues forcyclohexylamineandtriethylamineare 3.34 and 2.99, respectively. Which compound is the strongerbase? 12.20 The Kavalues Fordimethylamineanddiethylamineare 4.7 × 10−4and 3.1 × 10−...
原文指路:pKa Values in the Undergraduate Curriculum: What Is the Real pKa of Water? | Journal of Chemical Education (acs.org) 抽象的抽象的摘要:至少自 1960 年代以来,有机化学教科书附带的有机酸的pKa表中H2O和H3O+的值为15.74和-1.74,这在热力学和化学上是站不住脚的。在这里,我们将这个错误追溯至...
table with pKa values for a bunch of organic (and inorganic) molecules Here’s your typical pKa table with pKa values for a bunch of organic (and inorganic) molecules. You can find a table like that in any organic chemistry textbook. Your instructor has probably given you one of those.
The following table summarizes the pKa values of most functional groups in organic chemistry: Download the PDF file of the pKa Table below here, and this is a shorter version of the pKa table as well: You can use the table to look up the pKa value of a given compound based on the fun...
The importance of pKa values in organic chemistry can’t be overestimated, in my opinion. Not knowing pKa values in organic chemistry is like not knowing the value of the hands in poker. In this scheme, alkyl anions are the equivalent of the royal flush – they win the proton from every...
从这个角度看，定水为14，与所有热力学数据和实验结果都是匹配的，而且逻辑上也非常顺畅。搞一个15.7...
A very accessible account on the measurement of pKa values. [Sigificantly updated Oct 2022] 00General Chemistry Review 01Bonding, Structure, and Resonance 02Acid Base Reactions 03Alkanes and Nomenclature 04Conformations and Cycloalkanes 05A Primer On Organic Reactions ...
然而,如何将科学原理融入机器学习建模,以在有限训练数据下提升模型的预测性能,仍是一个重大挑战。在此背景下,深势科技推出了名为 Uni-pKa 的创新框架,将热力学原理融入机器学习建模中,并结合预训练-微调的训练策略,充分利用了不同质量的数据,实现了对酸解离常数(pKa)的高精度预测。