Here we report a thorough investigation on the anharmonic force fields of indole as well as the ab initio determinations of its gas phase basicity and aqueous pKa value. For the geometry optimizations, the calculations have been performed using both density functional (DFT) and second-order ...
Indole 3 aceto 9 5 Glutamine2 179 136 Cyclohexano 9 7 Histamine 5 09 76 Hexano 9 7 Hydroxyglutamic2 099 206 acid4 18 Amino Acids Hydroxyproline1 929 736 CompoundpKRef Leucine2 369 606 COOH NH3 Methionine2 289 21 Alanine2 359 696 1 Methylhistidine 6 48 1 69 8 856 Aminobutyric acid...
Finally, TRP-1 oxidizes DHICA to a carbonylated indole-quinone and produces melanin [2]. Various extracellular stimuli, including UV radiation, 3-isobutyl-1-methylxanthine (IBMX), alpha-melanocyte-stimulating hormone (α-MSH), Wnt-3a, and stem cell factor (SCF), can enhance melanin synthesis...
The acquisition of the 5-HT-dependent gene signature of human M-MØ is mediated by the 5-HT7R receptor. (A) Relative expression of the indicated genes in non-treated (-) or 5-HT-treated (5HT, 6 h) M-MØ and either in the absence (-) or in the presence of the 5-HT7R...