There is great interest in using theoretical methods to calculate pKa values for many different types of molecules. In this work, we used the QSPR approach: three parameters linear model is used for the calculation of the pKa values of three carboxylic acids namely Acetic acid, Benzoic acid ...
The pKa of carboxylic acids is ~5 and the pKa of phenol is ~10. Therefore, propionic acid is 105more acidic than phenol. What if there aremore functional groups in the molecule? Here, you need toidentify the most acidic proton in each molecule. In this case, molecule A is more acidic...
pKa of carboxylic acidThe pKa is the acid dissociation constant and describes the acidity of a particular molecule. The lower the value of pKa, the stronger the acid is. It results in a great ability to donate protons.Answer and Explanation: ...
Acid Benzoic Phthalic Isophthalic Terephthalic Hemimellitic Trimellitic Position of carboxyl pKI 1 1,2 1,3 1,4 1,2,3 1,2,4 4.17* 2.98* 3.46* 3.51* 2.80* 2.52* 5.87* 5.20* 8 Trimesic Mellophanic Prehnitic Pyromellitic Benzenepentacarboxylic Mellitic *ionic strength 0.03 **thermodynamic 1,3...
最全有机酸碱pKa值手册.pdf,pKa Data Compiled by R. Williams 1 pKa Values INDEX Inorganic 2 Phenazine 24 Phosphates 3 Pyridine 25 Carboxylic acids 4, 8 Pyrazine 26 Aliphatic 4, 8 Aromatic 7, 8 Quinoline 27 Phenols 9 Quinazoline 27 Alcohols and oxygen acids
化合物的pKa值 化合物的pKa值 pKa Values INDEX Inorganic2Phenazine24 Phosphates3Pyridine25 Carboxylic acids4, 8Pyrazine26 Aliphatic4, 8 Aromatic7, 8Quinoline27 Phenols9Quinazoline27 Alcohols and oxygen acids10, 11Quinoxaline27 Amino Acids12Special Nitrogen Compounds28 Peptides13Hydroxylamines28 Nitrogen ...
The pKa of COOH, or a carboxylic acid group, is between 3 and 5. Carboxylic acids have a low pKa due to resonant structures, and it can be lowered more through the inductive effect. Is a high pKa acidic or basic? A large pKa value usually means that a molecule is basic. A solution...
33、yclohexa necarboxylic acidsCl-2.94*3.83*3.99*Cyclohexa necarboxylic 4.902(CH 3)3Si-4.24*4.27*cis-1,24.802C2H 5O-4.21*4.17*4.45*cis-1,3cis-1,44.604.8422i-C 3H 7O-4.24*4.15*4.68*tran s-1,24.682n-C5H11O-4.55*tran s-1,34.822C6H 5-3.46*tran s-1,44.682CH 3CH 2-3.774.35*...
6.00 20 DL-Tartaric 3.03, --- 20 meso-1:2-Dimethylsuccinic 3.77, 5.36 20 meso-Tartaric 3.29, 4.92 20 *All are thermodynamic values Aliphatic Bicyclo[2.2.2]octane-1-carboxylic acids, 4substituted H- 6.75 2 C2H5O2C- 6.31 2 NC- 5.90 2 HO- 6.33 2 Br- 6.08 2 Lysergic acid, etc. er...
4.Molecular Topological Research on the Pka Values for Substituted Benzene Carbonic Acid;取代苯甲酸酸性Pka的分子拓扑研究 5.PKIB Inhibits cAMP-dependent Protein Kinase to Modulate Cell SenescencePKIB抑制PKA活性调节细胞衰老 6.Study on Selectivity of Inhibitor BD2 for PKA over PKC βⅡ抑制剂BD2对PKA与...