The assignment of pKa values to functional groups in amino acidsdoi:10.1016/0307-4412(94)00150-NIvan G DarveyBiochemical EducationDarvey IG. The assignment of pKa values to functional groups in amino acids. Wiley Online Library; 1995.
Protein pKa calculations In computational biology, protein pKa calculations are used to estimate the pKa values of amino acids as they exist within proteins.
Amino Acids, Peptides, and Proteins Titration of Amino Acids The pKavalues of thecarboxyl groupand the ammonium group of an amino acid, as well as the pHi, can be determined by titrating the conjugate acid withbase.Figure 14.2shows a typical titration curve for glycine. As base is added, ...
Decreased phosphosites in PKA-intact cells but not significantly changed in PKA-null cells showed typical basic amino acids (arginine [R] and lysine [K]) at position −2 and −3 (lower left). This motif is characteristic of basophilic kinases including PKA. There are also prominent acidic...
Figure 1: Time course of Yueju (YJ) and ketamine (KET) mediated antidepressant-like behavioral effects. Independent groups of mice were used at each time point and for each drug treatment, to avoid behavioral habituation. (A) Antidepressant activities in KM mice. Analysis of variance (ANOVA) ...
免疫细胞化学 (ICC/IF) 1:100-1:1,000 - 产品规格 种属反应 Human,Mouse,Rat 宿主/亚型 Rabbit / IgG 分类 Polyclonal 类型 Antibody 抗原 Recombinant protein encompassing a sequence within the center region of human PKA C alpha. The exact sequence is proprietary. ...
1. Three main groups of peptides and proteins were found: enzymes, including chitinase, peptidase S1, and LDLa-domain containing peptidase S1; moderately expressed non-enzymatic proteins; and novel peptides (xibalbins). Many of these peptides resemble inhibitor cysteine knot peptides (ICKs or ...
Enterotoxigenic Escherichia coli (ETEC) is the main causative pathogen of diarrhea. It causes acute watery diarrhea that leads to rapid dehydration and prostration within hours. ETEC is still an important cause of neonatal and post-weaning diarrhea in pigs. However, the mechanism underlying ETEC-indu...
For comparisons involving more than two groups of samples, statistical significance was evaluated by ordinary one-way ANOVA followed by Bonferroni post-hoc test. In vitro experiments involving normalization of treated on untreated conditions, controls are expressed as percentages or fold ± SD (unless ...
To investigate the energetics of release of the proton towards the proton-transfer pathways in PSII, we analyze the potential-energy profiles of the H-bonds between the ligand water molecules and the H-bond acceptor (i.e., the proton acceptor) groups in the PSII protein environment. The ...