氨基酸的等电点与pKa的关系
第22卷第1期 1996年1月 曲阜师范大学学报 JournalofQufuNormalUniversity Vol.22No.1 Jan.1996 氨基酸的等电点与pKa的关系 Ξ 刘崇凤付彩霞 (滨州医学院化学教研室,256603,山东省滨州市) 摘要根据氨基酸的电离平衡,讨论了碱性和酸性氨基酸的等电点与pKa的关系,得到 氨基酸的等电点的计算公式。 关键词电离平衡等...
Table 10lists pKavalues of severalDTTsbearing acidic or basic groups.DTT5-carboxylic acids (e.g.64) are rather strong acids, comparable todichloroacetic acid(98J(P2)387); in the case of the less-acidic 4-carboxylic acid (89a), analkyl groupin the 5-position unexpectedly lowers the pKavalu...
Hi,I had this question when I had to solve a problem where one point was which is more basic carboxylate anion or amino group. The pKa-s are 36 for amino and 3.7 for HCOOH, but one of the value is for NH3 and other for HCOOH, how to i get for HCOO- Logged Schrödinger...
CP binding specificity for the gRNA is critical for initiation of virion assembly and is R-domain dependent20,21. In the case of BBSV, recent studies have demonstrated that an N-terminal region enriched in basic amino acids (4KRNKGGKKSR13) is involved in CP nuclear locali- zation and ...
pH: pH is commonly used to express how basic or acidic a compound is on a scale of 0 to 14. 14 is very basic and 0 is very acidic, with 7 representing a neutral compound. It is a measure of the amount of free hydrogen in a solution. ...
The heart undergoes many changes as it progresses towards failure, one of which is the reactivation of the fetal gene program, resulting in the upregulation of β-MHC, ANP, and BNP gene expression [14]. Histone deacetylase 4 (HDAC4) is hypothesized to play a key role in the progression ...
PKA Inhibitor Fragment (6-22) amide is a PKA inhibitor peptide composed of 17 amino acids in a straight chain. In cellular biology, protein kinase A (PKA) is a family of enzymes whose activity depends on the cyclic AMP (cAMP) at the cellular level. PKA is also considered a cAMP depende...
pKa
A similar value was obtained with a PKI- derived peptide (amino acids 5-24), supporting our notion of related binding modes for these two peptides. These experiments demonstrate the direct interaction between ARHGAP36 and PKAC, mediated by a pseudosubstrate motif on ARHGAP36. ARHGAP36 inhibits...