The pK of acetic acid (CH3CO2H) is 4.8. Explain why the carboxylic acid group of Amoxicillin (pK=2.4), a synthetic penicillin, is more acidic than acetic acid, whereas the carboxylic acid group of indomethacin (pKa= 4.5), an anti-inflammatory analgesic used to treat rheumatoid arthritis, ...
The acidity of organic acids can be compared based on the stability of their conjugate bases. The pKa of picric acid is lower than the pKa of...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts ...
The differences may be explained by different temperature, ionic strength and analytical methods used. The accuracy of the method employed in this work was checked by phosphoric acid titrations. As mentioned before, a ±0.2 pKa value deviation may be expected in our results. Table 2. Macroscopic...
Overall, the results provide strong support for the notion of a three-factor structure of schizotypy, yet also indicate that different schizotypy measurements capture distinctive aspects of schizotypy. This finding indicates the necessity of an integrated approach when measuring the construct of schizotypy...
22.8 ml of acetic acid ad 1 l of H2O Ethidium Bromide Solution 1 g of ethidium bromide 100 ml of H2O 6× Deoxyribonucleic Acid (DNA) Test Buffer 250 mg of bromophenol blue 250 mg of Xylencyanol 33 ml of 150 mM Tris-HCl, pH 7.6 60 ml of glycerol 7 ml of H2β Isopropyl-β-D-...
Ssanghwa-tang (SHT) is a widely used medication for the treatment of fatigue, pain, inflammation, hypothermia, erectile dysfunction, cancer, and osteoporosis in Asia, however, role of SHT on the melanin synthesis has not been checked previously. Thus, the present study was designed to determine...
(Fig.1o), when compared to their respective controls. To gain further insights into the role of Eepd1 in different cell types within adipose tissue, we retrieved adipose tissue single-nucleus RNA sequencing (snRNA-seq) data for mouse samples from the curated RDS format files available on the...
As a result, this nitrogen-induced activation of trehalase was associated with induction of growth and progression over the 'START' point in the G1 phase of the cell cycle. By using temperature-sensitive mutants in cAMP synthesis at permissive and restrictive temperature it was...
Antisense compounds, compositions and methods are provided for modulating the expression of PKA regulatory subunit RII alpha. The compositions comprise antisense compounds, particularly antisense olig
S3A). As for 4F3HB, deprotonation of the p-hydroxyl group of 3F4HPA resulted in a small shift in the 19F resonance to less negative chemical shifts, in contrast with the effect of deprotonating the acetic acid group. pH dependence of the 19F signal of 3F4HPA in the presence of WT ...