Protein KinaseA protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them. Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins. The human genome...
Perry tries. She really does. And when I say tries, I mean tries everything she can to not do schoolwork and still pass. Like, when the three of us got together last night to complete the chemistry worksheets for our test today, Kirsten and I actually did the work while Perry sp...
Equation (1) relies on the definition of ΔG’a,sol(AH/BH+), which stands for the reduced basicity of base A− or B in solution and equals difference in the Gibbs energies of the neutral and protonated forms of the acid/conjugate base pair. Gsol(H+) is the Gibbs energy of the ...
The calculation of p𝐾apKa values is a common task in computational chemistry—it is therefore not surprising that there are many protocols available for various levels of theory [9]. The most common approach used for small molecules is based on the calculation of the difference in free energ...
The calculation of p𝐾apKa values is a common task in computational chemistry—it is therefore not surprising that there are many protocols available for various levels of theory [9]. The most common approach used for small molecules is based on the calculation of the difference in free energ...