除典型的Ser/Thr磷酸化位点,CRKs和第Ⅳ类CDPKs还具有Tyr磷酸化位点。CDPKs/CRKs可以被泛素化修饰。2 CDPKs/CRKs的表达模式和亚细胞定位转录组分析结果显示CDPKs具有不同的表达模式,表明CDPKs在植物细胞中功能的多样性。一些CDPK...
Eukaryotic-like protein Ser/Thr and Tyr kinases have only recently been discovered in prokaryotes. In most cases, their biochemical properties have been poorly characterized. The nitrogen-fixing and heterocyst-forming cyanobacterium Anabaena sp. strain PCC 7120 houses a family of eukaryotic-like Ser...
激酶是严格调节的关键酶,其通过将磷酸基团连接至受体而改变基质的性质,所述受体可以是小分子,脂质或蛋白质底物(至Ser,Thr或Tyr残基)。激酶参与信号转导途径并参与碳水化合物,脂质,核苷酸,氨基酸残基,维生素和辅因子的代谢。 蛋白激酶功能在从大肠杆菌到人类的进化上是保守的,并且在多种细胞过程中起作用,包括分裂,增...
yb-2896RPhospho-HER2 (Tyr877)磷酸化HER2受体抗体 yb-3358RPhospho-HSL (Ser660)磷酸化荷尔蒙敏感脂肪酶抗体 yb-5728RHURP肝癌上调蛋白抗体 yb-2145RHrasls3HRAS样抑制因子3抗体 yb-4193RCBS丝氨酸羧甲半胱氨酸合成酶抗体 yb-5727RHEC1癌细胞高表达蛋白Hec1抗体 ...
covalently modify Tyr227, we replaced the pyrazole ring in JH-VII-139-1 with a 3-benzenesulfonyl fluoride to generate a new compound, which we named SRPKIN-1. This substitution would potentially allow the formation of acovalent bondbetween thesulfonylfluoride group of SRPKIN-1 and Tyr227 of...
(Thr202/Tyr204), Erk, phospho-IKKa (Ser180)/IKKb (Ser181), IKKa, IKKb, IkBa, phospho-JNK (Thr183/Tyr185), JNK, phospho-c-Jun (Ser63), phospho-p38 (Thr180/Tyr182), p38, phospho-p65 (Ser536) and p65 (Cell Signaling Technology, Beverly, MA, USA); CDK2 and CDK4 (...
【方法】用生物信息学方法，在黄瓜的全基因组范围内鉴定CDPK 基因，并分析该基因的结构、染色体分布、进化关系及功能域。【结果】在黄瓜全基因组库中总共鉴定出17个CsCPKs ，被分为4类；所有CsCPKs 均含有6~8个内含子且都具有motif1~10，motif12和motif14；所编码氨基酸序列中含有4个EF -手型结构；多数CsCPKs ...
revealing an important role for PK-1 in promoting hyperphosphorylation of Ser and Thr residues and apparently priming p6.9 for Arg phosphorylation. Because some Arg and Ser/Thr phosphorylation was observed within p6.9 in the absence of PK-117, this suggests some redundancy among the p6.9-targeting...
Anti-Phospho- Beta-Catenin (Ser675) /FITC 荧光素标记兔抗人、大、小鼠磷酸化β 连环素蛋白抗体IgGX71667 0.2mlAnti-Phospho- Beta-Catenin (Thr41/Ser45) /FITC 荧光素标记兔抗人、大、小鼠磷酸化β 连环素蛋白抗体IgGX71668 0.2mlAnti- Gamma-Catenin/ Gamma-cats /FITC 荧光素标记γ-连环蛋白抗体(γ-...
磷酸化丝/苏氨酸蛋白激酶Plk1抗体 英文缩写: Phospho-PLK1 (Ser137) 磷酸化多聚合苷酸激酶3磷酸化酶抗体 英文缩写: Phospho-PNK1 (Ser114 + Thr118) 突触后密度蛋白93抗体 英文缩写: PSD93 磷酸化突触后密度蛋白93抗体 英文缩写: Phospho-PSD93 (Tyr340) 磷酸化突触后密度蛋白95抗体 英文缩写: Phospho-PSD95...