Different processes for preparing the derivatives are also described.BJOERK ANDERS KARL KONRADFEX TOMASOLSSON KNUT GUNNARABRAMO AINA LISBETHGUSTAFSSON BENGT KENNETH ROLANDCHRISTENSSON ERIK GUNNAR
mit der Maßgabe, daß 7-(6-[1,4]Diazepan-1-yl-2,2-dioxo-3,4-dihydro-2H-2λ6-benzo-[1,2,6]thiadiazin-1-ylmethyl)-napthalin-2-carboxamidin ausgeschlossen ist. 2. Verbindung nach Anspruch 1, wobei n 1 ist. 3. Verbindung nach Anspruch 2, wobei Z -(CRaRb)r- ist. ...
…Different processes for preparing the derivatives are also described.BJOERK ANDERS KARL KONRADFEX TOMASOLSSON KNUT GUNNARABRAMO AINA LISBETHGUSTAFSSON BENGT KENNETH ROLANDCHRISTENSSON ERIK GUNNAR
RANA AL HUSSAINY ET AL: " Design, synthesis and in vitro evaluation of bridgehead fluoromethyl analogs of-{2-[4-(2-methoxyphenyl)piperazin-1-yl]e thyl}--(pyridin-2-yl)cyclohexanecarboxamid e (WAY-100635) for the 5-HT1A receptor ", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS ...
Novel 1-piperazincarboxamidderivater substituted on the basic nitrogen atom and to pharmaceutical preparations and compositions containing them1-piparazinecarboxamide derivatives are described which have the formula (I) …… wherein R1 is a member selected from hydrogen, halogen or trifluoromethyl;… ...
amidinyl , carboxamido, cyano, hydroxyls, urea, -N ::: CH, = NCN, - (CH2) qOH, - (CH2) qOR31, - (CH2) qNH2, - (CH2) qNHR31, - (CH2) qN (R31 ) 2, - (CH2) qC (= O) NHR31, - (CH2) qSO2R31, - (CH2) qNHSO2R31, - (CH2) qSO2NHR31, -C (= S) N (H)...
A process for producing an N-tert-butyl-2-pyrazinecarboxamide represented by general formula (2) by the reaction of a cyanopyrazine represented by general formula (1) with tert-butyl alcohol in the presence of sulfuric acid; and a process for producing an N-tert-butyl-2-piperazinecarboxamide ...
Or exist independently, and if they exist, they are selected from the group of H, tar, alcoxi, alquenilo, carbon, cycloquilo and quilcloaloalquilo.cycloalkenyl, alkylaryl, arylalkyl, aryl, amino, alkylamino, amidinyl, carboxamido, cyano, hydroxyl, urea, -NsCH, = NCN, - (CH2) q...
heterocyclyl or heterocyclynyl; R1 and R2 are independently absent or present and if present, each is independently selected from the group consisting of H, alkyl, alkoxy, alkenyl, carbonyl, cycloalkyl, cycloalkenyl, alkylaryl, arylalkyl, aryl, amino, alkylamino, amidinyl , carboxamido, cyano...
Alcoxi,alquenilo carbonilo cicloalquilo alquilcicloalquilo-hydroxyalkyl, cycloalkenyl, alkylaryl, arylalkyl, aryl, amino, alkylamino, amidinyl, alkylamidinyl, carboxamido, cyano, hydroxyl, urea, -N ::: CH, = NCN, - (CH2) qOH, - (CH2) qOR31, - ( CH2) qNH2, - (CH2) qNHR31, ...