[4]Rosenstock J, Allison D, Birkenfeld AL, et al. Effect of additional oral semaglutide vs sitagliptin on glycated hemoglobin in adults with type 2 diabetes uncontrolled with metformin alone or with sulfonylurea: the PIONEE...
[3].Aroda VR, Erhan U, Jelnes P, et al. Safety and tolerability of semaglutide across the SUSTAIN and PIONEER phase IIIa clinical trial programmes[J]. Diabetes Obes Metab, 2023,25(5):1385-1397. doi:10.1111/dom.14990...
其优异的降糖疗效以及多重代谢获益已在系列Ⅲ期临床研究(PIONEER系列研究)中得到广泛证实,在与钠-葡萄糖共转运蛋白 2 抑制剂(SGLT2i)、二肽基肽酶-4抑制剂(DPP-4i)等新型口服降糖药物的头对头研究中,司美格鲁肽片均表现出更强的糖化血红蛋白(HbA1c)降幅,以及包括减重在内更优的综合代谢获益[5,6]。2019年至...
This trial is registered on ClinicalTrials.gov, number NCT02827708, and the European Clinical Trials Registry, number EudraCT 2015-005326-19, and is now complete. Findings: Between Sept 20, 2016, and Sept 29, 2017, of 721 patients screened, 324 were eligible and randomly assigned to oral ...
Global hotline for Ukrainian refugee patients participating in an Amgen clinical trial. Click here for more information. Our Products Amgen’s medicines treat serious illnesses and typically address diseases with a limited number of treatment options. ...
An Amgen-developed machine learning model, ATOMIC, is accelerating clinical trials to bring medicines to patients more quickly. Read Story ❮5/6❯ Science & Innovation04.09.2025 Unlocking Disease: Amgen's Omics Approach Advances Targeted Treatments ...
Global hotline for Ukrainian refugee patients participating in an Amgen clinical trial. Click here for more information. Our Story Watch VideoLearn more Our Science Amgen is a pioneer in the science of using living cells to make biologic medicines. ...
Global hotline for Ukrainian refugee patients participating in an Amgen clinical trial. Click here for more information. Our Story Watch VideoLearn more Our Science Amgen is a pioneer in the science of using living cells to make biologic medicines. ...
❮5/6❯ Science & Innovation04.17.2025 Follow the Data An Amgen-developed machine learning model, ATOMIC, is accelerating clinical trials to bring medicines to patients more quickly. Read Story ❮6/6❯ SCIENCE & INNOVATION04.08.2025 ...
"PIONEER III is the cornerstone of our extensive, international clinical trial program and I am very grateful for the support we have had from investigators around the world," said Dr.Jianhua Sun, PhD., chairman and chief executive officer of SINOMED. "Now...