mori. In this study, we identified a protein asteroid (BmAst) in silkworm B. mori, containing the PIN domain and XPG domain. BmAst gene was highest expressed in hemocytes and fat body of the 5th larvae. The BmAst gene expression was significantly induced by Bombyx ...
Wnt1英文名称:GAP-43 ( Growth associated protein-43 )白细胞介素-10受体a抗体 WWOX (WW domain-containing oxidoreductase)英文名称:Gastrin白细胞介素-13受体a1抗体 XIAP(X-linked Inhibitor of Apoptosis Protein)英文名称:AMACR/P504S(alpha-methylacyl-CoA racemase)免疫相关鸟苷三磷酸酶基因抗体 ...
The evolutive distribution of these proteins containing PIN-like domains as well as their organization and fusion with various functional domains is discussed and put in perspective with the diversity of functions they acquired during evolution, for the maturation and homeostasis of tRNA and a wider ...
The transforming growth factor (TGF)-β pathway inhibits the proliferation but promotes the metastasis of cancer95,96. The SMAD proteins are major downstream adapters of TGF-β signal and extensively recognized by WW domain-containing proteins, including Pin197,98. Initial research revealed that Pin1...
NADPH oxidase organizer 2; NCF 47K; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox organizing protein 2; NOXO2; p47 phox; p47phox; ;SH3 and PX domain containing protein 1A; SH3PXD1A; NADPH oxidase p47 phox; NCF1_HUMAN...
FBW7 (F-box and WD repeat domain-containing 7) or Fbxw7 is a tumor suppressor, which promotes the ubiquitination and subsequent degradation of numerous onc... L Wang,X Ye,Y Liu,... - 《Oncotarget》 被引量: 94发表: 2014年 Cognitive Effects of Cancer and Its Treatments at the Intersecti...
The hydrophilic domain is more divergent and it determines eight groups within the protein family. The activity of PIN proteins is regulated at multiple levels, including transcription, protein stability, sub- cellular localization and transport activity. Different endogenous and environmental signals can ...
Hes1 binds to the C-terminal WD40 repeat-containing domain of Gro/TLE1 through its own C-terminal tetrapeptide, WRPW.7,16 Complex formation with Hes1 results in Gro/ TLE1 recruitment to DNA,14,15 where Gro/TLE1 interacts with structural chromatin components.17 In addition, Hes1 binding ...
Introduction PINX1 is a common expressed protein that localizes to nucleoli and telomere speckles. PINX1 contains a Telomerase Inhibiting Domain that is caable of binding MCRS1, TERT and TERF1. PINX1 has been shown to be a potent telomerase inhibitor and putative tumor suppressor. PINX1 is re...
In accordance, a majority of known regulatory sites and peptide motifs locate to this central loop domain. Native protein separation of membrane protein fractions and in vivo crosslinking identified homo-oligomers made up of PIN1 and other canonical PINs37,38, overall implying formation of PIN ...