Pigment Cell Melanoma Res. 2022;35:369–386. |wileyonlinelibrary.com/journal/pcmr 369 |370 BROIT et al. While studies identifying genomic changes in AM have provided insight into the alterations contributing to tumorigenesis, they have generally included a small ...
REVIEW ARTICLE: How to make a melanoma: what do we know of the primary clonal events? 21 , 27 – 38 .↵ Bennett DC . How to make a melanoma: what do we know of the primary clonal events? Pigment Cell Melanoma Res. 2008 ; 21 ... Dorothy,C.,Bennett - 《Pigment Cell & ...
This monograph presents an up-to-date summary of recent therapeutic considerations in advanced and metastatic melanoma.Those approaches include surgery, radiotherapy, chemotherapy, immunotherapy, limb perfusion, monocl...
Interestingly, whensox10mutant cells are included, we observed that they were not separated from WT cells, but occupy part of the central cloud (Supplementary Fig.4b) and are effectively excluded from the differentiated pigment cell clusters. As expected given the strong failure of pigment cell fa...
Coloration and color patterning belong to the most diverse phenotypic traits in animals. Particularly, teleost fishes possess more pigment cell types than any other group of vertebrates. As the result of an ancient fish-specific genome duplication (FSGD)
Melanin pigment has a significant role in ocular pharmacokinetics, because many drugs bind at high extent to melanin in the retinal pigment epithelial cells. Most retinal pigment epithelial cell lines lack pigmentation and, therefore, we re-pigmented hum
RCM image-blocks were taken at four levels; stratum spinosum, basal cell layer, DEJ and dermis. All biopsy specimens showed increased amount of melanin in epidermis compared to perilesional skin. The hyperpigmentation of epidermis corresponded to highly refractile keratinocytes distributed in the s...
Cell culture and adenovirus infection Primary human umbilical vein endothelial cells (HUVECs) were collected and cultured as previously described [11]. The CT26 mouse colon carcinoma and B16-F10 mouse melanoma cell lines were purchased from the American Type Culture Collection (ATCC, Rockville Maryland...
(bisretinoids) of LGs. Photooxidized products of bisretinoids pose a much greater danger to the cell than non-oxidized one. Our studies of the fluorescent properties of LGs and their fluorophores (bisretinoids) showed for the first time that their spectral characteristics change (shift to the ...
Retinal cell transplantation in the macula: new techniques. Vision Res. 36, 4121–4125 (1996). 7. Binder, S. et al. Transplantation of autologous retinal pigment epithelium in eyes with foveal neovascularization resulting from age- related macular degeneration: a pilot study. Am. J. Ophthalmol....