Domestic pig Brain cell atlas Single-cell transcriptome Neural science 1. Introduction The pig brain (PB) has a higher correspondence to the human brain in terms of anatomy, physiology, and development compared with other commonly used small laboratory animals, such as mice and rats [1]. Recentl...
Cell-fate decisions during mammalian gastrulation are poorly understood outside of rodent embryos. The embryonic disc of pig embryos mirrors humans, making them a useful proxy for studying gastrulation. Here we present a single-cell transcriptomic atlas
www.nature.com/scientificreports OPEN Parallel single B cell transcriptomics to elucidate pig B cell repertoire Stanley Bram 1,2, Graeme Lindsey 1, Jenny Drnevich 3, Fangxiu Xu 3, Marcin Wozniak 4, Gisselle N. Medina 5,6 & Angad P. Mehta 1,2,7...
et al. A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff. Fly 6, 80–92 (2012). Article CAS PubMed PubMed Central Google Scholar Liu, X. et al. GWAS Atlas: an updated knowledgebase integrating more curated associations in plants and animals. ...
www.nature.com/scientificreports OPEN Parallel single B cell transcriptomics to elucidate pig B cell repertoire Stanley Bram 1,2, Graeme Lindsey 1, Jenny Drnevich 3, Fangxiu Xu 3, Marcin Wozniak 4, Gisselle N. Medina 5,6 & Angad P. Mehta 1,2,7...
Pigs play a central role in human livelihoods in China, but a lack of systematic large-scale whole-genome sequencing of Chinese domestic pigs has hindered genetic studies. Here, we present the 1000 Chinese Indigenous Pig Genomes Project sequencing datase
Cell landscapes and differential nutrient absorption preferences of porcine intestines based on single-cell transcriptome profiles.AThe Seurat algorithm and t-SNE plot were used to visualize the cell subtypes of all 23,133 intestinal cells.BExpression heatmaps of the top 5 cell type-specific genes ...
Single-Cell Transcriptomic Atlas of Primate Ovarian Aging. Cell. 2020;180(3):585-600.e519. 51. Zhao ZH, Ma JY, Meng TG, Wang ZB, Yue W, Zhou Q, Li S, Feng X, Hou Y, Schatten H, et al. Single-cell RNA sequencing reveals the landscape of early female germ cell development....
1d–e, Extended Data Fig. 2a–e and Supplementary Table 4). We further analyzed 270 multi-omics datasets in pigs, including 245 whole-genome bisulfite sequencing (WGBS; Supplementary Figs. 4 and 5 and Supplementary Tables 5–7), 20 single-cell RNA-seq (Supplementary Fig. 6 and ...
The results were incorporated into Expression Atlas as baseline studies. Additionally, we report a comparative analysis of protein expression across pig and human tissues among other analyses. 2. Methods 2.1. Data Sets The PRIDE database hosted 165 publicly available MS proteomics data sets of Sus ...