(c-Met) mTOR signaling pathway Validated targets of C-MYC transcriptional activation C-MYC pathway Validated targets of C-MYC transcriptional repression N-cadherin signaling events Nectin adhesion pathway Nephrin/Neph1 signaling in the kidney podocyte Role of Calcineurin-dependent NFAT signaling in ...
基因:MAGEA6,P53,P16,PCNA,Paxillin,C-myc,TGF-B1。如何做他们的pathway 分析,怎么使用cytoscap...
Finally, to rule out the possibility that immortalisation by the SV40 large T antigen specifically impacted on the phenotype under these conditions, we also performed colony-forming assays with c-Myc/Ras-transformed MEF and exposed them to IR. However, these MEF seemed actually even more ...
In this study, we investigated the pathway of caspase-2 activation during apoptosis induced by NO in E1A-expressing cells. Our data show that caspase-2 is the initiator caspase in response to NO injury and is required for NO-induced mitochondrial injury. NO induces processing of PIDD from PI...
PHM induced apoptosis via downregulation of anti-apoptotic (survivin, B-cell lymphoma Extra-large; BCL-XL, X-linked inhibitor of apoptosis protein; XIAP, Myelocytomatosis; C-myc), metastatic (Matrix metallopeptidases 9/2; MMP9/2), and cell-cycle regulatory (cyclin D1 and E) proteins, ...
JAK3, MAP2K1 (MEK1), MAPK1 (ERK2), MAPK14, MAPK3 (ERK1), MAPK8 (JNK1), MTOR, MYC...
Targeting MYC for the treatment of breast cancer: use of the novel MYC-GSPT1 degrader, GT19630 Minhong Tang John Crown Michael J. Duffy Research Open access 28 January 2025 Synergistic antitumor effect of MK-1775 and CUDC-907 against prostate cancer Saisai Ma Yichen Xu Yang Zhan Rese...
Quarfloxin, a G4-interactive compound targeting the c-MYC G4–nucleolin complex. As previously described, Quarfloxin and Pidnarulex (Fig. 1) were originally derived from a group of fluoroquinolones that were shown to have dual Top2 and G4 interactions, and QQ58 was the starting structure fo...
Androgen Receptor Aromatase CD20 CD52 c-Myc CPT1 c-RET CTLA-4 Decarboxylase Dehydrogenase FPR GLUT Glutaminase HIV ProteaseAnti-infection HSP90 Hydroxylase IAP IgE IRE1 LDL Lipase Lipoxygenase Lysyl Hydroxylase MT Receptor NADPH oxidase others P2 Receptor PAFR PCSK9 RAAS RANK Ligand Reverse Transcripta...
2022-Scientific Reports-IF(4.38)DJ‑1 upregulates the Nrf2、GPX4 signal pathway to inhibit trophoblast ferroptosis in t... pdf下载 >> · 2022-Journal of Cancer Research and Clinical Oncology-IF(4.32)Targeting NAD metabolism regulates extracellular adenos... ...