A small but significant number of skin cancers are malignant melanomas. Malignant melanomais a highly aggressive cancer that tends to metastasizerelatively early and aggressively, thereby spreading to other parts of the body. These cancers may be fatal if not found and treated early. Like many can...
Novel pyrrolopyrimidines as Mps1/TTK kinase inhibitors for breast cancer New targeted therapy approaches for certain subtypes of breast cancer, such as triple-negative breast cancers and other aggressive phenotypes, are desired... Y Sugimoto,DB Sawant,HA Fisk,... - 《Bioorg Med Chem》 被引量:...
The most serious and dangerous cancers are metastatic cancers. Metastasismeans that the cancer has spread from the place where it started into other tissues distant from the original tumor site. The most common place for breast cancer to metastasizeis into the lymph nodesunder the arm or above t...
First Pictures of BRCA2 Protein Show How it Repairs DNAScientists have taken pictures of the BRCA2 protein for the first time, showing how it works to repair damaged DNA. Mutations in the gene that encodes BRCA2 are well known for raising the risk of breast cancer and other cancers....
Invasive, or infiltrating, ductal carcinoma; invasive, or infiltrating, lobular carcinoma; medullary carcinoma; Paget's disease; and inflammatory breast cancer are all cancers that afflict the human body. Several rare types can strike people as well. Invasive, or infiltrating, ductal carcinoma is ...
around the breast nipple, mostly in women, and rarely in men. The skin of the nipple is red and scaly and may itch. In most cases, an underlying breast cancer is also present (and felt as a lump). Treatment is by surgical removal of the breast and lymph nodes in the related armpit...
A woman's odds of developing ovarian cancer are higher if a close relative has had cancer of the ovaries, breast, orcolon. Researchers believe that inherited genetic changes account for 10% of ovarian cancers. This includes the BRCA1 and BRCA2 gene mutations, which are linked tobreast cancer...
There are three types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma. Most skincancersare locally destructive cancerous (malignant) growth of the skin. They originate from the cells of the epidermis, the superficial layer of the skin. Unlike cutaneous malignantmelanoma...
Air Pollution Could Be Raising Your Odds for a Blood Clot Blood Test Might Alert Doctors to Problem Drinking Newer Drug Could Be Advance Against Tough-to-Treat Breast Cancers Too Many Babies Still Sleep in Positions That Raise SIDS Risk ...
We’ve looked at liver, lung and breast cancers. We have some compounds that we think work really well when we test them in cells. We think we understand how they’re working, but it would be nice to understand exactly what’s going on. What is the exact target?You’ll do assays an...