Here we report the cryo-EM structures of human PI3KC3-C1 and PI3KC3-C2 at sub-nanometer resolution. The two structures share a common L-shaped overall architecture with distinct features. EM examination revealed that PI3KC3-C1 "stands up" on lipid monolayers, with the ATG14L BATs domain ...
LY294002 抑制纯化的 PI3K,IC50 为 1.4 µM。图链接 294002化学结构LY 294002基础信息中文名:2-吗啉代-8-苯基色酮;2-吗啉代-8-苯基色酮;;PI3K 抑制剂;PI3-激酶抑制剂;英文名:LY294002;LY-294002;PI3-kinase inhibitorCAS号:154447-36-6结构式:O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4...
中文名:2-吗啉代-8-苯基色酮;2-吗啉代-8-苯基色酮;;PI3K 抑制剂;PI3-激酶抑制剂; 英文名:LY294002;LY-294002;PI3-kinase inhibitor CAS号:154447-36-6 结构式:O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4 分子式:C19H17NO3 分子量:307.34 ...
中文名:2-吗啉代-8-苯基色酮;2-吗啉代-8-苯基色酮;;PI3K 抑制剂;PI3-激酶抑制剂; 英文名:LY294002;LY-294002;PI3-kinase inhibitor CAS号:154447-36-6 结构式:O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4 分子式:C19H17NO3 分子量:307.34 ...