PI3K-AKT-GSK3 beta-CREB signaling pathwayThe medial prefrontal cortexWortmanninBackground: Alcohol abuse and anxiety disorders often occur concurrently, but their underlying cellular mechanisms remain unclear. Neuroadaptation within the medial prefrontal cortex (mPFC) have been implicated in the molecular ...
Berberine regulates melanin synthesis by activating PI3K/AKT, ERK and GSK3β in B16F10 melanoma cells Hyun MY, Lim YY, Song KY and Kim BJ: Berberine regulates melanin synthesis by activating PI3K/AKT, ERK and GSK3β in B16F10 melanoma cells... Y Song,Y Lee,H Kim,... - 《...
We hypothesized that PI3K/Akt/GSK-3 signaling pathway could be involved in this apparent age-dependent neuroprotective/neurodegenerative status. In fact, our data demonstrated that, as compared with age-matched nontransgenic controls, the Ser-9 phosphorylation of GSK-3 was increased in the 6-month...
PI3K/Akt/GSK3 beta signallingLearning and memoryProtective efficacy of curcumin in arsenic induced NMDA receptor dysfunctions and PI3K/Akt/ GSK3 beta signalling in hippocampus has been investigated in vivo and in vitro. Exposure to sodium arsenite (in vivo - 20 mg/kg, body weight p.o. for ...
These results suggest that Prx II regulated apoptosis of keratinocytes via the PI3K/AKT/GSK3 & beta; signaling axis. Furthermore, treatment with the Prx II inhibitor Conoidin A significantly alleviated psoriatic symptoms in IMQ model mice. These findings have important implications for developing ...
TDCPP protects cardiomyocytes from H2O2-induced injuries via activating PI3K/Akt/GSK3 beta signaling pathwayTDCPPCardiomyocytesOxidative stressCalcium overloadApoptosisTris (1, 3-dichloro-2-propyl) phosphate (TDCPP) is a major type of organophosphorus flame retardants, and long-term exposure to TDCPP to...
Infiltrating mast cells promote renal cell carcinoma angiogenesis by modulating PI3K AKT GSK3β AM signalingOncogene advance online publication, January 23 2017. doi:10.1038/onc.2016.44 ...doi:10.1038/onc.2016.442Y ChenC LiH XieY FanZ Yang
They gradually decreased to 2.1 ±0.2 mg/1 at 3 weeks. Thisafter, the values increased and reached the maximal level at 8 weeks (4.9 ±0.5 mg/1). The pattern of the mean values for reticulocyte counts was similar; 1.3 ± 0.2% at diagnosis, 0.3 ±0.05% at 2 weeks and 4.7 ±1.3% ...
Miao, He,Yu,etc.Role of PI3K/Akt/NF-κB and GSK-3β pathways in the rat model of cardiopulmonary bypass-related lung injury.[J].2018,106(Spec).He M, Zhang Y, Xie F, Dou X, Han M, Zhang H. Role of PI3K/Akt/NF-kappaB and GSK-3beta pathways in the rat model of ...
Role of connexin-43 in protective PI3K-Akt-GSK-3beta signaling in cardiomyocytes. Am J Physiol Heart Circ Physiol 302: H2536-H2544, 2012.Ishikawa S,Kuno A,Tanno M,et al.Role of connexin-43 in protec- tive PI3 K-Akt-GSK-3^ signaling in cardiomyocytes[J].Am J Physiol Heart Cire ...