One of the class I lipid kinase members of the PI3K family, p110伪, is probably the most commonly mutated kinase in the human genome. Alongside genetic, molecular biological, and biochemical studies, chemical inhibitors have been extremely helpful tools in understanding ...
英文名:LY294002;LY-294002;PI3-kinase inhibitor CAS号:154447-36-6 结构式:O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4 分子式:C19H17NO3 分子量:307.34 闪点:253.0±28.7 °C 熔点:183-185℃ 沸点:494.6±45.0 °C at 760 mmHg
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摘要: The kinase mammalian target of rapamycin (mTOR) is the second molecular target, the first being vascular endothelial growth factor (VEGF) or its receptor (VEGFR2), for which drugs have been developed关键词:Renal cell carcinoma PI3-kinase Akt mTOR Temsirolimus Everolimus ...
Taken together, our results demonstrated that lupeol could target to activate PI3-kinase/Akt pathway and promote tumor cell growth at low doses. Combination therapy of lupeol and a PI3-kinase inhibitor, S14161, could synergistically enhance the antitumor effect of lupeol in vitro and in vivo. Th...
LY 294002 , PI3-kinase inhibitor 是一种选择性磷脂酰肌醇 3-激酶 (PI3K) 抑制剂,其效力是槲皮素的 2.7 倍。 LY294002 抑制纯化的 PI3K,IC50 为 1.4 µM。 货品编码规格纯度价格 (¥)现价(¥)特价(¥)库存描述数量总计 (¥) YZM001122-10mg10mg99%¥ 938.00¥ 938.001-3days ...
PI3-Kinase a Inhibitor 2 供应商 Cayman Chemical 产品货号 10010177-10 产品报价 ￥询价/10mg 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 产品新闻 背景资料 Cayman Chemical是生化小分子标准品专家,艾美捷作为中国区域总代理,提供Cayman Chemic...
中文别名 154447-38-8;PI3-激酶抑制剂;PI3激酶抑制剂; 英文别名 LY 303511;154447-38-8;PI3-kinase inhibitor;LY303511;8-Phenyl-2-(1-piperazinyl)-4H-chromen-4-one CAS号 154447-38-8 SMILES O=C1C=C(N2CCNCC2)OC3=C(C4=CC=CC=C4)C=CC=C13 Inchi InChI=1S/C19H18N2O2/c22-17-13-18(21-...
产品编号:9901S查看说明书 产品名称:LY294002 (PI3 Kinase Inhibitor) .0订购此产品 供应商:CST 规格:1.5 mg 目录价:661 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址:点击查看详细 打印此页关闭此页 上一个:PD98059 (MEK1 Inhibitor)[9900S/1.5 mg] ...
(Verheijen, J. C. and Zask, A., Phosphatidylinositol 3-kinase (PI3K) inhibitors as anticancer drugs, Drugs Fut. 2007, 32(6): 537-547). Exelixis Inc. (So. San Francisco, CA) recently filed INDs for XL-147 (a selective pan-PI3K inhibitor of unknown structure) and XL-765 (a mixed ...