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Retinal photoreceptors are neurons that convert dynamically changing patterns of light into electrical signals that are processed by retinal interneurons and ultimately transmitted to vision centers in the brain. They represent the essential first step in seeing without which the remainder of the visual s...
Part I Human Organization 1 Organization of the Body 2 Chemistry of Life 3 Cell Structure and Function 4 Body Tissues and Membranes 5 The Integumentary System Part II Support and Movement 6 The Skeletal System 7 The Muscular System Part III Integration and Coordination 8 The Nervous System 9 Th...
Microglia are resident cells of the brain involved in regulatory processes critical for development, maintenance of the neural environment, injury and repair. They originate from erythromyeloid progenitors (EMPs) in the yolk sac and develop in the formin
The lung is the interface between air and blood where the exchange of oxygen and carbon dioxide occurs. The surface liquid that is directly exposed to the
whereas the basolateral (serosal) membrane faces toward the interstitium. Both membranes have distinct roles due to their localization and differential expression of proteins (Fig.1a). The basolateral membrane uptakes nutrients, ions and oxygen from the blood, and disposes of the cellular waste produ...
we summarize the current literature on a highly conserved sub-family of oxygenases that catalyze protein histidyl hydroxylation. We discuss the evidence supporting the biochemical assignment of these emerging enzymes as ribosomal protein hydroxylases, and provide an overview of their role in immunology,...
The purpose of this paper is to investigate the muscle metabolic response to TRs abrogation, by using two different mouse models of global TRα- and TRβKO. In line with the clinical features of resistance to THs syndromes in humans, characterized by THRs gene mutations, both animal models ...
cells Review Fluorescent, Bioluminescent, and Optogenetic Approaches to Study Excitable Physiology in the Single Cardiomyocyte Connor N. Broyles 1,2, Paul Robinson 1,2 and Matthew J. Daniels 1,2,3,4,5,* ID 1 Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of ...