Physiological and Pathological Functions of TMEM30A: An Essential Subunit of P4-ATPase Phospholipid Flippasesdoi:10.1155/2023/4625567DRUG discoveryPHOSPHATIDYLSERINESMEMBRANE proteinsKNOCKOUT micePROTEIN structurePhospholipids are asymmetrically distributed across mammalian plasma membrane. The function ...
Physiological and pathological functions of the prion protein homologue Dpl 来自 Semantic Scholar 喜欢 0 阅读量: 35 作者:Axel,Behrens 摘要: A misfolded version of the prion protein PrP(C), known as PrP(Sc), is the major component of scrapie infectivity, the pathological agent in transmissible ...
TMEM106B, encoding a lysosome membrane protein, has been recently associated with brain aging, hypomyelinating leukodystrophy and multiple neurodegenerative diseases, such as frontotemporal lobar degeneration (FTLD) and limbic-predominant age-related TDP-43 encephalopathy (LATE). During the past decade, ...
Physiological and pathological functions of the prion protein homologue Dpl To date, at least 900 different microRNA (miRNA) genes have been discovered in the human genome. These short, single-stranded RNA molecules originate from ... Axel,Behrens - 《Br Med Bull》 被引量: 50发表: 2003年 Ph...
fundamental role in the function of various organs under normal and abnormal conditions. About this article Cite this article Gu, Y., Gu, C. Physiological and Pathological Functions of Mechanosensitive Ion Channels.Mol Neurobiol50, 339–347 (2014). https://doi.org/10.1007/s12035-014-8654-4 ...
Abnormal NPP expression is involved in pathological mineralization, crystal depositions in joints, invasion and metastasis of cancer cells, and type 2 diabetes. In this review we summarize the present knowledge on the structure and the physiological and biochemical functions of E-NPP and their ...
with NMT1 playing a critical role in these physiological and pathological processes.154,155,156During apoptosis, caspases cleave NMTs, causing NMT1 to move from the PM to the cytosol and relocate NMT2 in the opposite direction,157and this positional change may influence its substrate specificity....
Steroid hormones affect physiological and pathological reactions of the immune system and can either positively or negatively influence immunopathological-associated diseases. Estrogens,progesterone,and androgens directly and indirectly modify numerous immunological functions. Estrogens drive differentiation of CD4 ...
It www.intechopen.com Physiological and Pathological Aspects of Human NK Cells 339 has been hypothesized that they may recognize HLA-I molecules loaded with viral or tumor peptides, or, with low affinity, normal HLA-I molecules. In this latter case, when target cells selectively down-regulate ...
studies have linked NOX3 to physiological and pathological processes outside the inner ear. In this chapter we summarize key discoveries related to the expression pattern, interacting partners, physiological functions, and pathological effects of NOX3. ...