Members of the fibroblast growth factor (FGF) ligand family play a critical role in mesoderm formation in the frog Xenopus laevis. While many components of the signaling cascade triggered by FGF receptor activation have been identified, links between these intracellular factors and the receptor itself...
The two amino-terminal SH2 domains of ZAP-70 bind the dually tyrosine phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) domains of ITAM-containing receptors (Hatada et al., 1995, Cambier, 1995). In T cells, the primary ITAM-containing receptor is the T lymphocyte antigen ...
It can make it hard to think clearly and cause problems with memory, focus, and productivity. But science has more to say about it. The most common symptoms of brain fog are feeling tired all the time, difficulty concentrating or focusing on tasks, memory problems, trouble finding the right...
The amino acid sequence of MutH purified using the Impact I system was identical to native MutH. Preparation of DNA Substrates The oligonucleotides 5′-GGTACCGAGTTCGAATTCG-3′ and 5′-GGTACCGAGCTCGAATTCG-3′ were used to generate covalently closed duplex M13mp18 DNA containing a single G-T ...
To explore the functions of the BLNK SH2 domain, we employed a Syk-driven yeast two-hybrid screen, which could identify novel phosphotyrosine-dependent binding partners for BLNK in B cells. Such molecules could provide links between BLNK and the JNK or p38 pathways. We isolated multiple ...
Compared with the sodium alginate/chitosan single-network hydrogel crosslinked by electrostatic interactions, sodium alginate/chitosan/Zn2+ double-network hydrogels exhibit better mechanical properties, excellent antibacterial ability, and has the potential to become a new wound dressing. It provides ...
Numerous polysaccharides are capable of gelation through various physical cross-links, especially hydrogen bonding, owing to their abundant functional groups, such as hydroxyl, carboxyl and amino groups. The common gelling polysaccharides are alginate, agar, carrageenan, curdlan, gellan gum, konjac ...