To identify proteins that physically and functionally interact with Smad2, we screened a bacteriophage expression library using radiolabeled Smad2 as probe. We have identified calmodulin as a Smad2-interacting protein; we demonstrate that the association is calcium-dependent and requires amino acids between...
To explore the functions of the BLNK SH2 domain, we employed a Syk-driven yeast two-hybrid screen, which could identify novel phosphotyrosine-dependent binding partners for BLNK in B cells. Such molecules could provide links between BLNK and the JNK or p38 pathways. We isolated multiple ...
arginylglycylaspartic acid;immobilization;surface functionalization;hydroxyapatite;APTES;FBS;cell adhesion 1. Introduction New designs of biomaterials based on the association of peptides and proteins with hydroxyapatite (HA, Ca10(PO4)6(OH)2) have been considered to increase osteoconductivity and promote...
[15]. However, a notable finding in our study was that variations in CRP levels did not affect the proposed effects of adherence to a healthy diet on sarcopenia risk. Thus, our findings indicate that the observed links between dietary patterns and SRS are not influenced by variations in CRP...
It links up with the endocannabinoid system to keep your body calm. CBD also triggers the release of endorphins that help your body in relaxation. The other condition this cannabis compound can be used to manage is cancer. It suppresses the growth or spread of cancerous cells in the body....
The amino acid sequence of MutH purified using the Impact I system was identical to native MutH. Preparation of DNA Substrates The oligonucleotides 5′-GGTACCGAGTTCGAATTCG-3′ and 5′-GGTACCGAGCTCGAATTCG-3′ were used to generate covalently closed duplex M13mp18 DNA containing a single G-T ...
(a) Schematic illustration of the nos-3 pre-mRNA and the nos-3(Δ) mutation. Boxes, exons; lines, introns; blue, putative CCHC zinc fingers (each is indicated as a block); dark grey, minimal region required for interaction with FBF-1 (amino-acid residues 429–681; see Figure 2); ...