While proton radiation therapy offers substantially better dose distribution characteristics than photon radiation therapy in certain clinical applications, data demonstrating a quantifiable clinical advantage is still needed for many treatment sites. Unfortunately, the number of patients treate...
Intensity modulated radiation therapyPhotonsAuditory system modelsTissuesPurpose:The increased sparing of normal tissues in intensity modulated proton therapy (IMPT) in pediatric brain tumor treatments should translate into improved neurocognitive outcomes. Models were used to estimate the intelligence quotient ...
A comprehensive plan evaluation based on radio-biological models should be carried out to decide if a lung patient would really be benefit from proton therapy.doi:10.1002/acm2.12281Xiao, ZhiyanZou, Wei JChen, TingYue, Ning JJabbour, Salma K...
and for pediatric patients where the risk for late toxicity or radiation-associated malignancy is the highest [53, 59,60,61]. Although there are no large well-matched trials comparing photon to proton therapy for sarcomas yet, many retrospective data analyses and phase II trials suggest promising...
摘要: Compared with photon radiation (XRT), proton beam radiation therapy (PBRT) reduces dose to normal tissues, which may lead to better neurocognitive outcomes. We compared change in intelligence quotient (IQ) over time in pediatric patients with brain tumors treated with PBRT versus XRT....
and for pediatric patients where the risk for late toxicity or radiation-associated malignancy is the highest [53, 59–61]. Although there are no large well- matched trials comparing photon to proton therapy for sarcomas yet, many retrospective data analyses and phase II trials suggest promising ...
The role of IL-6 in the radiation response of prostate cancer. Radiat Oncol 2013; 8: 159. 41 Holliday EB, Frank SJ. Proton radiation therapy for head and neck cancer: a review of the clinical experience to date. Int J Radiat Oncol Biol Phys 2014; 89: 292–302. 42 Ding L, Li B,...
a comparative study betweenproton therapy, IMRT and VMAT for paediatric patients with brain tumours regarding the risk of radiation-induced second cancers revealed that IMRT and VMAT presented similar and the highest lifetime attributable risks (0.05–4.9%), while proton therapy was associated with th...
estimate and compare the risk of radiation-induced adverse late effects in pediatric patients with medulloblastoma (MB) treated with either three-dimensional conformal radiotherapy (3D CRT), inversely-optimized arc therapy (RapidArc (R) (RA)) or spot-scanned intensity-modulated proton therapy (IMPT)...
Although a CDSS was previously applied [34], [35], we have not found any application that could make quantitative decision-making about photon vs. proton therapy at three levels. A key characteristic of the system is its parallel pipeline structure, which allows easy extension by reusing the ...