We do the following for fixing a brain sample for imaging photo-labeled neurons under the confocal microscope. Note: Each row of the culture plate is numbered, from 1 to 12, and each column is labeled with a letter, from A to F. We refer to each well by its respective number and ...
However, the therapy of this type of hemorrhage is limited, and new strategies are needed to reduce hematoma expansion. Here we show that the meningeal lymphatics is a pathway to remove red blood cells from the brain’s ventricular system of male human, adult and newborn rodents and is a ...
An image compared the alleged "drinker’s brain" with a "non-drinker’s brain" to expose the harmful effects of alcohol.
Understanding how protein–protein interaction networks in the brain give rise to cognitive functions necessitates their characterization in live animals. However, tools available for this purpose require potentially disruptive genetic modifications and
Robust estimates of the positions of the labeled points were obtained from the median values across all the frames of the locomotion period present in the video. Those values were then averaged across the videos belonging to a given disease stage. To identify locomotion periods, we used the x-...
Caption Illustration of the cranial nerves anatomy. The cranial nerves are a set of 12 paired nerves that arise directly from the brain. The first two nerves (olfactory and optic) arise from the cerebrum, whereas the remaining ten emerge from the brainstem. The names of the cranial nerves rel...
To start the thrombolytic test, the targeting specificity of B@SP−C NPs to thrombus was examined in ex vivo blood clots. The artificial blood clots were prepared by mixing fresh mice blood with thrombin, and the NPs were labeled with a NIR dye, 1,1′-dioctadecyl-3,3,3′,3′-...
There is a growing emphasis being placed on the potential for cuffless blood pressure (BP) estimation through modelling of morphological features from the photoplethysmogram (PPG) and electrocardiogram (ECG). However, the appropriate features and models
This review covers advancements in biosensing, biophotovoltaics, and photobiomodulation, focusing on the synergistic use of light, biomaterials, cells or tissues, interfaced with photosensitive dye-sensitized, perovskite, and conjugated polymer organic semiconductors or nanoparticles. Integration of semiconduct...
Because BGAG attaches selectively to SNAP and MAG (maleimide-azobenzene-glutamate) to an introduced cysteine, SNAP-mGluR2 and GluK2(L439C) could be co-expressed and separately labeled, each with its own photoswitch. When AAVs that deliver SNAP-mGluR2 and LiGluR to RGCs were mixed and injec...